诊断前的身体活动和宫癌的死亡率:全国性的队列研究
Jun-Hyeong Seo1, Young Eun Chung1, Seongyun Lim1
1Sungkyunkwan University School of Medicine, Samsung Medical Center, Department of Obstetrics and Gynecology, Gynecologic Cancer Center, Seoul, Republic of Korea.
概括
诊断前的身体活动,特别是较高的总能耗,与宫癌患者的更好的生存率有关. 这种益处在患有局部疾病的老年妇女 (≥65岁) 中最为明显.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 在宫癌诊断之前,身体活动的预后价值尚不清楚.
- 了解这种关联可以为癌症患者提供生活方式建议.
研究的目的:
- 调查诊断前身体活动与被诊断患有宫癌的女性全因死亡率之间的关系.
- 确定特定的患者亚组,他们可能从体力活动中获益最多.
主要方法:
- 一项基于人口的队列研究分析了8833名被诊断患有宫癌的韩国妇女的数据.
- 身体活动是自我报告的,并根据强度,持续时间和总能耗 (MET-分钟/周) 分类.
- 用Cox比例危险模型评估全因死亡率,并根据癌症阶段和年龄对子组进行分析.
主要成果:
- 较高的体力活动总能耗与所有原因死亡率的降低有关.
- 活动水平在500-1499MET分钟/周之间,与<500MET分钟/周相比,死亡率显著降低.
- 剧烈的强度活动和定期炼与局部宫癌妇女的较低死亡率有关,特别是65岁以上的妇女.
结论:
- 诊断前增加的体力活动与局部宫癌女性的生存率提高有关.
- 身体活动的预后意义似乎在患有局部疾病的老年女性 (≥65岁) 中最相关.
- 这些发现凸显了身体活动在特定宫癌患者亚组中的潜在预后作用.
相关概念视频
Appendicitis-II: Diagnostic Studies and Management
586
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
586
Aneurysm II: Clinical Manifestations and Diagnostic Studies
371
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
371
Acute Pyelonephritis II: Diagnostic Studies and Management
432
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
432
Hypertension III: Clinical Manifestations and Diagnostic Studies
585
Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
585
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
349
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
349
Acute Coronary Syndrome III: Diagnostic Studies
285
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
285


