开发和验证一个名图,以预测长期的残留头持续至少7天后,良性发性定位的发展和验证
Yu Liu1, Shulin Li1, Hongmei Zhang1
1Department of Neurology, Beijing Anzhen Nanchong Hospital of Capital Medical University & Nanchong Central Hospital, 97 South Renmin Road, Shunqing District, Nanchong City, 637100, Sichuan, China.
概括
这项研究创建了一个名图,用于预测良性发性定位 (BPPV) 患者的长期头. 老年,糖尿病和抑郁症增加风险,而前体康复训练有助于预防.
科学领域:
- 神经学 神经学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 医疗信息学 医疗信息学
背景情况:
- 良性发性位置性 (BPPV) 是导致头的常见原因.
- 在初始BPPV治疗后,残留的头可能会持续数天或数周.
- 预测持续的头对于患者管理和资源分配至关重要.
研究的目的:
- 在BPPV患者中开发和验证持续≥7天的残留头的预测性名录.
- 确定与BPPV后长期头相关的关键临床因素.
主要方法:
- 对907名BPPV患者的回顾性分析.
- 使用LASSO和多变量逻辑回归开发一个名图.
- 使用单独的患者队列验证名录的验证.
主要成果:
- 高龄,糖尿病和抑郁症是导致长期头的重要危险因素.
- 门康复训练成为一种保护因素.
- 在训练 (0.836) 和验证 (0.802) 两组中,名图显示出强大的预测性能,AUC值高.
结论:
- 开发的诺米图是用于识别长期残留头风险较高的BPPV患者的实用工具.
- 该模型结合了年龄,DM,抑郁症和前体康复训练.
- 通过校准和决策曲线分析证实了临床效用.
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