在前列腺癌的积极监测中基于MRI的病变大小测量的间和内度变化:一项多中心研究
Cameron Englman1,2, Busola Adebusoye3,4, Michele Cosenza5,6
1Division of Surgery & Interventional Science, University College London, London, UK. cameron.englman.21@ucl.ac.uk.
European radiology
|February 6, 2026
概括
在MRI上测量前列腺癌病变大小是不可靠的,放射科医生和方法之间存在很大的差异. 评定器内可靠性更好,这表明放射科医生应该重新测量病变,以进行一致的积极监测监测.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 前列腺癌 (PCa) 管理通常涉及积极监测 (AS).
- 在MRI上精确测量PCa病变对于AS决策至关重要.
- 目前的方法包括最大直径,双轴直径和体积计算 (圆公式,平面测量).
研究的目的:
- 在基线MRI扫描上评估不同PCa病变大小测量方法的inter-和intra-rater可靠性.
- 评估放射科医生对活跃监测患者测量的变异性.
主要方法:
- 包括20名患有MRI可见的PCa病变的活跃监测中的患者.
- 五位放射科医生使用四种方法独立测量指数损伤:最大直径,双轴直径,圆体积和平面体积.
- 在4周的时间间隔后重复测量,以评估评价者内部的可靠性.
主要成果:
- 在所有方法和阅读器中观察到损伤大小测量的显著变化.
- 单个病变的测量跨越了临床显著性和不显著性疾病的值.
- 随着病变变大,评价者之间的可靠性下降,而评价者内部的可靠性通常更好.
结论:
- 在AS的MRI上可靠测量PCa病变仍然具有挑战性.
- 评定者内部的可靠性超过了评定者间的可靠性,突出了放射科医生重新测量病变的重要性.
- 需要进行进一步的研究,以提高连续MRI扫描中追踪病变大小变化的准确性.
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