个性化炼计划对老年风湿性关节炎患者的身体功能的影响,这些患者患有高风险的肉症:随机对照试验的结果
Mie Torii1,2, Akira Onishi3,4, Ryuji Uozumi5
1Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Arthritis research & therapy
|February 7, 2026
概括
个性化炼治疗没有显著改善老年类类风湿性关节炎患者的身体功能,这些患者有患类的风险. 然而,它在站立能力,握力和心理健康方面显示出潜在的好处.
科学领域:
- 老年学是一门学科.
- 类风湿病学 类风湿病学
- 运动生理学 运动生理学
背景情况:
- 类风湿性关节炎 (RA) 患者与普通人群相比,面临更高的肉症风险.
- 众所周知,运动疗法可以改善老年人的肌肉力量,但其在RA患者的有效性尚未完全确立.
- 这项研究侧重于年龄较大的RA患者,他们有高风险患上肉症.
研究的目的:
- 评估16周个性化炼计划对老年RA患者的身体功能的有效性.
- 评估运动治疗对这种特定患者群体中与肉症相关的结局的影响.
主要方法:
- 一个优越性随机对照试验,涉及140名RA患者,年龄在60-85岁之间,有萨科佩尼亚风险.
- 干预组 (n=69) 接受了为期16周的个性化炼计划,以及营养指导和标准护理.
- 对照组 (n=65) 仅接受营养指导和标准护理. 主要结局是短物理性能电池 (SPPB) 评分的变化.
主要成果:
- 干预组和对照组之间在初级结果 (SPPB总分数的变化) 中没有显著差异 (0.2分差,p=0.206).
- 二次结果显示,在16周后,椅子站测试,握力和心理组件得分的改善趋势.
结论:
- 16周的个性化炼计划没有显著改善老年RA患者的整体身体功能 (SPPB分数),这些患者有高风险患上肉症.
- 干预可以为身体功能的特定方面提供好处,包括站立能力和握力,以及与心理健康有关的生活质量.
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