儿科患者短肠综合征的治疗结果
Ha Huy Khoi1, Ngo van Bach2,3, Dang Hoang Khanh Duy4
1Phongkhamnhidrthieu, Ho Chi Minh City, Vietnam.
Journal of paediatrics and child health
|February 7, 2026
概括
保护结肠和大肠 (ICV) 显著改善了患有短肠综合征 (SBS) 的儿童的治疗成功. 保持足够的残留小肠长度 (RSBL) 对儿科SBS患者的积极结果至关重要.
科学领域:
- 儿科手术 儿科手术
- 胃肠病学 胃肠病学
- 临床结果研究研究
背景情况:
- 短肠综合征 (SBS) 是一种复杂的疾病,需要手术干预.
- 肠道解剖学,包括残留小肠长度 (RSBL) 和大肠 (ICV) 状态,在SBS治疗中至关重要.
- 了解解剖特征的预后价值对于优化儿科SBS护理至关重要.
研究的目的:
- 评估SBS的儿科患者的特定肠道解剖特征和治疗结果之间的关联.
- 确定切除肠段,残留小肠长度 (RSBL) 和大肠 (ICV) 保存对SBS治疗成功的影响.
- 确定改善儿科SBS治疗结果和减少住院治疗的关键预后因素.
主要方法:
- 对35名小儿SBS患者的回顾性分析,这些患者在2021年7月至2024年7月期间接受了小肠切除.
- 根据RSBL的SBS定义,预期寿命的≤25%或依赖门营养的≥60天.
- 将治疗结果分类为成功 (稳定,出院) 或不成功 (死亡,缺乏改善).
主要成果:
- 整体治疗成功率为60%,40%的患者死亡或失败.
- 成功组的RSBL平均值 (86.1厘米) 与失败组的RSBL平均值 (52.7厘米;p < 0.001) 相比,在成功组的RSBL平均值显著更长 (86.1厘米).
- 结肠和ICV的保存与治疗成功有显著的关联 (p <0.05),而ICV保存的缺乏导致了更长的住院时间.
结论:
- 结肠和大肠 (ICV) 的保存是改善儿科短肠综合征 (SBS) 结果的关键预后因素.
- 保持足够的残留小肠长度 (RSBL) 对于成功治疗和降低儿科SBS的死亡率至关重要.
- 保存肠道的解剖结构,如结肠和ICV可以减少住院时间,并提高患者的整体康复.
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