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Updated: Feb 8, 2026

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亚优化器:用于结构导向设计强效和选择性激酶基质的计算工作流

Abeeb A Yekeen1,2, Cynthia J Meyer1,2, Melissa McCoy1

  • 1Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas 75390-9038, United States.

Journal of chemical information and modeling
|February 7, 2026
PubMed
概括

我们开发了Subtimizer,这是一种用于设计酶基质的AI管道. 这种工具增强了基质活性和特异性,有助于激酶研究和药物发现.

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