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Updated: Feb 8, 2026

Using Ustilago maydis as a Trojan Horse for In Situ Delivery of Maize Proteins
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静电特洛伊木马:带电 Pleuromutilin 突破了对抗生素耐药细菌中绑架核糖体的阳离子屏障

Lei Tian1,2,3, Boxin Zhang1,2, Bingxing Zhang1,2

  • 1School of Biological and Pharmaceutical Sciences, Shaanxi University of Science & Technology, Xi'an 710021, PR China.

ACS infectious diseases
|February 7, 2026
PubMed
概括

一种新型抗生素,PNY-6b,使用静电学来克服具有阴离子包裹的病原体的耐药性. 这种带电的肺素有效地向核糖体,改善了感染中的生存率.

关键词:
抗微生物耐药性 抗微生物耐药性细菌包裹的屏障是细菌包裹的屏障.酸性抗生素是一种抗生素.电静电互补性 电静电互补性基转移酶中心 (PTC)这是一种多性木质素.

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