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Updated: Feb 8, 2026

Chromatin Interaction Analysis with Paired-End Tag Sequencing ChIA-PET for Mapping Chromatin Interactions and Understanding Transcription Regulation
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染色体可访问性动态和转录调节在Tetrahymena thermophila中

Tengfei Hu1, Zhengyu Luo2, Xiaoyuan Song3

  • 1Hefei National Research Center for Physical Sciences at the Microscale, MOE Key Laboratory for Cellular Dynamics, Center for Advanced Interdisciplinary Science and Biomedicine of IHM, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, 230026, China.

Science China. Life sciences
|February 7, 2026
PubMed
概括

在Tetrahymena thermophila中,染色体的可访问性主要是转录起始点 (TSS) 的上游,与人类细胞不同. 这种上游偏差是单细胞真核生物的祖先特征,揭示了染色体组织的进化变化.

关键词:
泰特拉希米纳热 (Tetrahymena thermophila) 是一种热的植物.ATAC-seqq 的使用情况.染色质可访问性 染色质可访问性表观遗传调节 表观遗传调节转录法规 转录法规 转录法规 转录法规

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