没有纹身的乳腺癌辅助放射治疗:表面成像和四点定位之间的比较
C Lenci1, F De Felice1, M Tomaciello1
1Radiation Oncology, AOU Policlinico Umberto I, Department of Radiological, Oncological and Pathological Sciences, "Sapienza" University of Rome, Rome, Italy.
概括
与传统纹身相比,表面导向放射治疗 (SGRT) 在右侧乳腺癌放射治疗定位方面提供了更高的准确性和可重复性. 这种非侵入性方法改善了患者的体验和治疗精度.
科学领域:
- 辐射瘤学 辐射瘤学
- 医学物理 医学物理
背景情况:
- 精确的患者定位对于右侧乳腺癌的有效放射治疗至关重要.
- 传统的基于纹身的设置可能会导致患者的痛苦,可能缺乏精度.
- 表面导向放射疗法 (SGRT) 为患者对齐提供了一个非侵入性的替代方案.
研究的目的:
- 为了比较SGRT的准确性和可重现性与传统的基于纹身的定位对右侧乳腺癌RT.
- 为了评估两个定位方法之间的设置错误和分数间的变化.
主要方法:
- 预期单中心交叉研究设计.
- 在52名患者中比较SGRT (AlignRT) 和基于纹身的定位.
- 使用圆束CT注册和统计分析 (沙皮罗-威尔克,t测试) 来量化设置错误.
主要成果:
- 与基于纹身的定位相比,SGRT在所有方向 (纵向,垂直,横向) 的平均设置错误明显较低 (纵向和垂直的P < 0.001,横向的P = 0.044).
- SGRT表现出减少的分数间变化和较少的异常值 (>1厘米).
- 通过SGRT观察到优越的设置稳定性.
结论:
- 与AlignRT相结合的SGRT为右侧乳腺癌放射治疗中的患者定位提供了更高的准确性和可重复性.
- 这种非侵入性方法提高了治疗精度,减少了设置变化,并通过消除纹身来提高患者舒适度.
- 建议进行进一步的研究以验证发现并评估长期结果.
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