相关实验视频
Updated: Feb 9, 2026

14:57
DNA Stable-Isotope Probing DNA-SIP
Published on: August 2, 2010
45.2K
在分解过程中人类皮肤的稳定同位素 (δ13C, δ15N, δ34S)
Ryan Pawlowski1, Shari L Forbes2, Paul Szpak1
1Department of Anthropology, Trent University, 1600 W Bank Dr, Peterborough, ON K9L 0G2, Canada.
Forensic science international
|February 7, 2026
概括
人体皮肤的稳定同位素分析可以帮助估计自死亡以来的时间. 隔离有机化合物显示出对死后间隔估计的更多希望,而不是分析散装皮肤.
科学领域:
- 法医科学 法医科学 法医科学
- 生物地质化学生物地质化学
- 稳定同位素分析方法
背景情况:
- 在法医调查中,估计死后间隔至关重要.
- 目前的分解时间表方法在后期阶段缺乏准确性.
- 像皮肤这样的耐用组织的稳定同位素分析显示了死亡估计后的时间.
研究的目的:
- 为了研究人类皮肤在分解过程中的稳定同位素 (δ13C, δ15N, δ34S) 变化.
- 评估化学脂质提取和蛋白质溶解对同位素分析的影响.
- 为了确定最佳的样品预处理,观察与分解相关的同位素变化.
主要方法:
- 在几个月的时间里,从一个分解设施收集了人类皮肤样本.
- 在皮肤样本上进行了稳定同位素分析 (δ13C, δ15N, δ34S).
- 一个2x2的因数设计检查了脂质提取和蛋白质溶解的效果.
主要成果:
- 在大量皮肤样本中,分解改变了δ13C和δ15N.
- 分解副产品和化学预处理之间的相互作用揭示了温度和衰变状态的关系.
- 观察到与分解进展相关的同位素变化.
结论:
- 虽然散装皮肤显示出同位素变化,但隔离特定的有机化合物提供了一种更敏感的方法来跟踪分解.
- 对特定化合物同位素分析的进一步研究有望改善死后间隔估计.
- 这项研究突出了法医分解分析的新方法.
相关概念视频
Isotopes
64.8K
Elements have a set number of protons that determines their atomic number (Z). For example, all atoms with eight protons are oxygen; however, the number of neutrons can vary for atoms of the same element. The sum of the number of protons and the number of neutrons is the mass number (A). Atoms with the same atomic number but different mass numbers are called isotopes. Elements can have multiple isotopes, for example, carbon-12, carbon-13, and carbon-14.
An element's atomic mass, or weight,...
An element's atomic mass, or weight,...
64.8K
Synthesis and Decomposition Reactions
38.3K
Synthesis and decomposition are two types of redox reactions. Synthesis means to make something, whereas decomposition means to break something. The reactions are accompanied by chemical and energy changes.
38.3K
Elements: Chemical Symbols and Isotopes
126.6K
A chemical symbol is an abbreviation used to indicate an element or an atom of an element. For example, the symbol for mercury is Hg. The same symbol is used to indicate one atom of mercury (microscopic domain) or to label a container of many atoms of the element mercury (macroscopic domain).
Some symbols are derived from the common English name of the element; others are abbreviations of the name in another language — Latin, Greek or German. For example, the symbol for aluminum (common name)...
Some symbols are derived from the common English name of the element; others are abbreviations of the name in another language — Latin, Greek or German. For example, the symbol for aluminum (common name)...
126.6K
Isotopes and Radioisotopes
12.7K
In the early 1900s, English chemist Frederick Soddy realized that an element could have atoms with different masses that were chemically indistinguishable. These different types are called isotopes — atoms of the same element that differ in mass. Isotopes differ in mass because they have different numbers of neutrons but are chemically identical because they have the same number of protons. Soddy was awarded the Nobel Prize in Chemistry in 1921 for this discovery.
An isotope containing...
An isotope containing...
12.7K
Mass Spectrometry: Isotope Effect
4.3K
Most elements exist in nature as a mixture of isotopes. The isotopes differ in weight due to their respective number of neutrons. The molecular weight of a molecule is different depending on the specific isotope of its elements involved. As a result, the mass spectrum of the molecule exhibits peaks from the same fragment at multiple positions. The positions of these mass signals depend on the mass differences between isotopes. Furthermore, the intensity of these signals is dependent on the...
4.3K
Skin Cancer
5.9K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.9K

