解开PTSD和MDD:检查创伤集中治疗期间症状的时间变化
Alexander C Kline1, Juan Diego Vera2, Laura D Crocker1
1Psychological Health and Readiness, Naval Health Research Center, San Diego, CA, United States of America; Leidos, San Diego, CA, United States of America.
治疗创伤后应激障碍 (PTSD) 症状可能是减少伴随性病例中主要抑郁症 (MDD) 症状的关键. 首先解决创伤后应激障碍可能会导致现役服役人员抑郁症的结果更好.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
- 军人心理健康 军人心理健康
背景情况:
- 重度抑郁症 (MDD) 和创伤后应激障碍 (PTSD) 经常同时发生.
- 在创伤集中治疗期间,伴随性PTSD和MDD的症状变化的时间序列尚不清楚.
研究的目的:
- 检查PTSD和抑郁症症状变化之间的时间关系,在患有并发性PTSD和MDD的个体中.
- 调查认知处理疗法 (CPT) 或带有行为激活 (BA+CPT) 的CPT是否影响这些时间动态.
主要方法:
- 使用了分散的交叉滞后多层模型.
- 在一项随机临床试验中,分析了78名美国现役服役人员的每周症状数据.
- 核心PTSD症状和认知情感/体质抑郁症症状集群被检查.
主要成果:
- 在核心PTSD和抑郁症症状之间发现了强烈的双向人际影响.
- 在人体内,核心PTSD症状的减少显著预测了随后的认知情感和体质抑郁症状的减少.
- 反向关系 (抑郁症预测PTSD) 不显著.
结论:
- 对于患有并发性PTSD和MDD的服务人员来说,针对PTSD症状似乎更为关键,以改善抑郁症,而不是相反.
- 这些发现表明,应优先考虑PTSD治疗,以实现更广泛的症状缓解.
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