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Updated: Feb 9, 2026

Highly Sensitive and Quantitative Detection of Proteins and Their Isoforms by Capillary Isoelectric Focusing Method
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Highly Sensitive and Quantitative Detection of Proteins and Their Isoforms by Capillary Isoelectric Focusing Method

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对于与疾病相关的异构体,表面活性剂蛋白C成熟的不同途径

Sarah Bui1, Anamarie Reineberg2, Dakota Jones3

  • 1Pulmonary and Critical Care Division, Department of Medicine; Perelman School of Medicine at the University of Pennsylvania; Philadelphia, PA 19104; PENN-CHOP Lung Biology Institute; Perelman School of Medicine at the University of Pennsylvania; Philadelphia, PA 19104.

The Journal of biological chemistry
|February 7, 2026
PubMed
概括

突变表面活性蛋白C (SP-C) I73T错误地进入细胞表面,与野生型SP-C不同,由于处理受损. 贩运和成熟的这种差异,涉及类蛋白转化酶,有助于肺部疾病.

关键词:
膜细胞2型细胞戈尔吉戈尔吉是一座古老的城市.蛋白转化酶的使用方法蛋白质成熟 蛋白质成熟表面活性蛋白C 表面活性蛋白C

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