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Updated: Feb 9, 2026

Analysis of Cardiac Contractile Dysfunction and Ca2+ Transients in Rodent Myocytes
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在高空暴露后,MOTS-c通过促进线粒细胞吸收来减轻心脏功能障碍

Zihang Feng1, Yuan Xing2, Jing Lou3

  • 1Key Laboratory of Aerospace Medicine of the Ministry of Education, School of Aerospace Medicine, Fourth Military Medical University, Xi'an 710032, China; Department of Cardiovascular Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, China.

Free radical biology & medicine
|February 7, 2026
PubMed
概括

由于线粒体问题和缺乏MOTS-c,高海拔暴露会导致持久的心脏功能障碍. 补充MOTS-c (12S核糖体RNA类型-c的线粒体开放读取框架) 可以在去适应过程中保护心脏.

关键词:
心脏保护 保护心脏脱适应变化 脱适应变化暴露于高海拔地区的高空暴露.这就是MOTS-cc.线粒细胞衰变 (mitophagy) 是一种神经衰变的过程.

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