相关实验视频
Updated: Feb 9, 2026

07:14
Acupuncture in a Rat Model of Asthma
Published on: August 25, 2020
6.6K
孕期喘生物治疗的安全性
Madeline S Kellam1, Jeffrey M Chambliss1, Luyu Xie2
1Division of Allergy and Immunology, Departments of Internal Medicine and Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas.
The journal of allergy and clinical immunology. In practice
|February 7, 2026
概括
怀孕期间适度至重度喘的生物疗法显示,不良结果的风险降低. 这项研究发现,生物制剂可能为患有喘的孕妇提供保护作用.
科学领域:
- 产科和妇科 产科和妇科
- 肺部病理学 肺部病理学
- 药理学 药理学是指药理学的学科.
背景情况:
- 怀孕期间控制不良的喘与母亲和新生儿的不良结果有关.
- 生物药物,如单克隆抗体,有效地管理中度至重度喘,但它们的怀孕安全数据有限.
研究的目的:
- 为了比较中度至重度持久性喘患者的不良妊娠结果,医生处方生物药与未暴露,匹配的队列.
主要方法:
- 使用TriNetX美国协作网络进行回顾性队列研究.
- 包括孕妇 (15-44岁) 患有中度至重度喘 (2010-2025年).
- 1:1倾向性得分匹配比较生物使用者与未暴露的对照者,分析母亲和胎儿的并发症.
主要成果:
- 匹配组 (每组535名患者) 在生物组显示妊娠不良结果的风险降低 (OR 0.609,CI 0.460-0.807,p=0.001).
结论:
- 在怀孕期间治疗中度至重度喘的生物学使用与增加不良结果无关.
- 在这个人群中,生物药物可能会减少不良妊娠结果.
相关概念视频
Asthma-I: Introduction
3.5K
Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.5K
Survey Safety
413
Surveying near highways, rough terrain, or power lines involves significant risks. Working along highways is particularly dangerous and requires the use of warning signs and flagmen. It is safest to avoid working directly on roads and use offsets whenever possible. When highway work is unavoidable, it must follow all safety guidelines. Surveyors should wear bright clothing, such as orange reflective vests, to ensure visibility to motorists, coworkers, and hunters. In construction zones, wearing...
413
Asthma-III: Symptoms and Complications
3.4K
Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma
Classification of Asthma
3.4K
Asthma-IV: Diagnostic and Management
3.2K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.2K
Asthma: Pathogenesis and Management
1.4K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.4K
Asthma-II: Pathophysiology and Classification
4.4K
Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
4.4K

