科里尼细菌周围假肢关节感染:一个单一机构与病毒性生物体的经验
Jennifer C Wang1, H Sadiyya Ingawa1, Brenna E Blackburn1
1Department of Orthopaedics University of Utah, Salt Lake City, UT, USA.
The Journal of arthroplasty
|February 7, 2026
概括
由Corynebacterium引起的周围假肢关节感染 (PJIs) 由于抗生素耐药性而具有挑战性. 然而,手术和传染病团队之间的协作管理可以在这些困难的情况下带来合理的结果.
科学领域:
- 整形外科手术 整形外科手术
- 传染性疾病 传染性疾病
- 微生物学 微生物学
背景情况:
- 周围假肢关节感染 (PJIs) 的结果取决于治疗,宿主因素和感染生物体.
- 克拉姆阳性细菌Corynebacterium很少涉及PJIs,但由于抗生素耐药性,它会给治疗带来挑战.
- 关于专门由Corynebacterium引起的部或膝盖PJIs的管理数据有限.
研究的目的:
- 报告有关管理部或膝盖PJIs的机构经验,由Corynebacterium属引起.
- 分析这些感染的人口,手术和临床结果.
主要方法:
- 从2016年到2023年对患有Corynebacterium PJI的患者进行了回顾性评估.
- 纳入标准:全部或膝盖关节整形手术,已确定Corynebacterium属.
- 收集的数据:人口统计,之前的手术,感染特征,治疗和结果.
主要成果:
- 确定了18名患者 (平均年龄65岁,女性94.4%),平均有4.9次之前的手术.
- 大多数感染是多药耐药的Corynebacterium (57.9%之前的PJI).
- 16/18患者避免了截肢,15/18患者没有再感染,12/18患者在平均2.9年的随访中仍然活着.
结论:
- 与Corynebacterium相关的PJIs是由于抗生素耐药性的独特挑战.
- 有效的管理需要外科和传染病专家之间的密切合作.
- 通过适当的多学科护理,可以实现合理的患者结果.
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