在异性慢性鼻炎中嗅觉球体体积和功能恢复
Keisuke Yamamoto1, Masaki Abukawa2, Tsuyoshi Okuni1
1Department of Otolaryngology-Head and Neck Surgery, Sapporo Medical University School of Medicine, Sapporo, Japan.
The Laryngoscope
|February 7, 2026
概括
嗅觉球体体积 (OBV) 增加了经过手术以治疗异性慢性鼻炎 (ECRS),与改善的嗅觉识别相关. 更长的气味持续时间和更高的症状得分预测了较小的OBV增加,这表明结构变化与嗅觉恢复有关.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 神经学 神经学
- 放射学 放射学是一门学科.
背景情况:
- 乳性慢性鼻炎 (ECRS) 显著影响嗅觉功能.
- 嗅觉球体体积 (OBV) 的变化可能反映疾病的严重程度和治疗反应.
研究的目的:
- 在ECRS患者中评估OBV和嗅觉功能的术后变化.
- 用3T MRI和嗅觉测试来评估OBV变化与嗅觉功能之间的关联.
主要方法:
- 对32名接受功能性内镜外科手术的ECRS患者进行了回顾性观察研究.
- 通过多项测试 (Alinamin,T&T,OE,OSIT-J,VAS,SAOQ) 评估术前和术后的嗅觉功能.
- 从3T MRI FIESTA序列手动测量OBV;用于分析的后勤回归.
主要成果:
- 在术后嗅觉识别 (OE,OSIT-J) 和症状评分 (VAS,SAOQ) 中观察到显著改善.
- 在术后,平均OBV增加了10.3% (p=0.095).
- OBV变化与嗅觉识别改进相关 (OE,OSIT-J);更长的气味持续时间和更高的SAOQ分数预测了较小的OBV增加.
结论:
- 使用FIESTA的3T MRI提供了ECRS中嗅觉变化的结构相关值.
- OBV变化与术后嗅觉识别相关,这表明与功能恢复有联系.
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