相关实验视频

Updated: Feb 9, 2026

In Vitro Method to Study Sex-Based Differences in Conjunctival Goblet Cells
06:28

In Vitro Method to Study Sex-Based Differences in Conjunctival Goblet Cells

Published on: July 28, 2023

856

人体膜上皮细胞衍生的外体miR-25-3p通过降低BCL2L11的调节来增强结膜杯细胞中的粘素表达

Yanming Zhang1, Wenjia Wu1, Ting Meng2

  • 1School of Medical Technology and Nursing, Shenzhen Polytechnic University, Shenzhen, 518055, Guangdong, China.

Scientific reports
|February 7, 2026
PubMed
概括

携带miR-25-3p的人类羊上皮细胞 (hAEC) 衍生外体促进MUC5AC的产生,并减少结膜杯细胞的亡. 这表明外体miR-25-3p通过调节粘素表达和细胞存活来支持眼睛表面的健康.

关键词:
结膜杯细胞是结膜杯细胞.外基因组是外基因组的组成部分.人类羊膜上皮细胞在 MUC5ACAC 中.在 miR-25-3p 中使用.

更多相关视频

Isolation, Cryopreservation and Culture of Human Amnion Epithelial Cells for Clinical Applications05:31

Isolation, Cryopreservation and Culture of Human Amnion Epithelial Cells for Clinical Applications

Published on: December 21, 2014

14.4K
Tear-Derived Exosomal miR-15a as New Diagnostic Tool for Diabetic Retinopathy07:45

Tear-Derived Exosomal miR-15a as New Diagnostic Tool for Diabetic Retinopathy

Published on: December 30, 2025

421

相关概念视频

Cell Specific Gene Expression01:58

Cell Specific Gene Expression

Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...
16.6K
Cell Specific Gene Expression01:58

Cell Specific Gene Expression

5.6K
Receptor Downregulation in MVBs01:15

Receptor Downregulation in MVBs

Multivesicular bodies (MVBs) are mature endosomes that sort ubiquitinated proteins and then fuse with lysosomes to degrade the sorted proteins. Epidermal growth factor (EGF) and its receptor (EGFR) form a complex that can be internalized through endocytosis, sorted into an MVB, and later degraded.
The EGFR can initiate signaling pathways that  lead to cell proliferation, migration, and differentiation. Overexpression of EGFR  stimulates cells to proliferate. Excessive  EGFR...
2.8K
Adult Stem Cells01:33

Adult Stem Cells

Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
33.9K
Overview of Exosomes01:36

Overview of Exosomes

Exosomes are stable, lipid bilayer-enclosed vesicles capable of crossing biological barriers. They can carry a wide range of molecules required for intercellular communication. Once exosomes are released from the cell where they originated, they enter a recipient cell through various pathways such as fusion, receptor-mediated endocytosis, macropinocytosis, and phagocytosis.
Stahl et al. discovered exosomes in 1983, but the exosomes were initially considered waste products released from the...
3.7K
mRNA Stability and Gene Expression02:51

mRNA Stability and Gene Expression

The structure and stability of mRNA molecules regulates gene expression, as mRNAs are a key step in the pathway from gene to protein. In eukaryotes, the half-life of mRNA varies from a few minutes up to several days. mRNA stability is essential in growth and development. The absence of the proteins regulating its stability, such as tristetraprolin in mice, can cause systemic issues, including bone marrow overgrowth, inflammation, and autoimmunity.
Cis-acting Elements involved in mRNA stability
6.7K