Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Retrieval01:12

Retrieval

450
Retrieval is the process of getting information out of memory storage and back into conscious awareness. This ability is essential for daily tasks like brushing hair and teeth, driving to work, and performing job duties. Retrieval occurs in three ways: recall, recognition, and relearning.
Recall involves accessing information without cues, such as during an essay test, where individuals must retrieve facts and concepts from memory unaided. Another example is remembering the name of a colleague...
450
ER Retrieval Pathway01:45

ER Retrieval Pathway

4.8K
In the secretory pathway, vesicles transport proteins from one cellular compartment to another in forward transport to deliver the protein to its correct location. Occasionally, misfolded proteins and incorrect proteins escape their original compartments, and a retrieval pathway is used to return the escaped proteins to their original compartment.
The ER uses many checkpoints to prevent the entry of incorrectly folded or a resident protein as cargo onto a transport vesicle. These mechanisms...
4.8K
Plasmids01:28

Plasmids

2.6K
Plasmids are extrachromosomal DNA molecules found in bacteria, archaea, and some eukaryotic microbes like yeast. These small, circular DNA structures typically contain fewer than 30 genes, although some may exist linearly. Plasmids vary in their number within a cell, known as copy number. Single-copy plasmids are present in one copy per cell and multi-copy plasmids are present in multiple copies, reaching over 100 copies per cell.Plasmids usually replicate independently of the chromosomal DNA...
2.6K
Design Example: Alignment of a Road Line Using GIS01:17

Design Example: Alignment of a Road Line Using GIS

350
The alignment of a road line using Geographic Information Systems (GIS) is a critical process in civil engineering, combining advanced technology with practical decision-making. This methodology begins with the collection of geospatial data, including information on land cover, geomorphology, drainage patterns, slope, and contour details. Such data is typically acquired through satellite imagery and GIS tools, offering a comprehensive understanding of the terrain.Once the data is gathered, it...
350
Cis-regulatory Sequences02:02

Cis-regulatory Sequences

11.9K
Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...
11.9K
Sequences01:29

Sequences

281
Sequences are fundamental mathematical objects consisting of ordered lists of numbers that follow a specific rule or pattern. Sequences are critical in various mathematical concepts, including calculus, series, and number theory. They can model real-world phenomena such as population growth, financial investments, and physical processes like the diminishing height of a bouncing ball.Each number in a sequence is referred to as a term. Typically, the terms are denoted as a1, a2, a3,…, where...
281

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Linkage-aware inference of fitness from short-read time-series genomic data.

Virus evolution·2026
Same author

PhaBOX2: an enhanced web server for discovering and analyzing viral contigs in metagenomic data.

Nucleic acids research·2026
Same author

A metatranscriptome based approach to predict multidrug resistance phenotypes in Klebsiella pneumoniae without culturing.

Journal of global antimicrobial resistance·2026
Same author

Fast and accurate identification of emerging viral reassortment from genome sequences.

Nucleic acids research·2026
Same author

PhaGCN_Cluster: A Scalable and Robust Framework for Automated Classification and Discovery of Viral Dark Matter from Metagenomes.

Interdisciplinary sciences, computational life sciences·2026
Same author

Unraveling the activity of phage-carrying antibiotic resistance genes in constructed wetlands.

Frontiers in cellular and infection microbiology·2026
Same journal

Somatic mobility of transposons is explosive and shaped by distinct integration biases in Arabidopsis thaliana.

Genome biology·2026
Same journal

UK Biobank whole-genome sequencing reveals robust contributions of rare variants to complex-trait heritability.

Genome biology·2026
Same journal

A one-week automated genome-wide optical pooled screen using OttoSeq.

Genome biology·2026
Same journal

Integrated lipidomic and transcriptomic profiling of the host response in human malaria.

Genome biology·2026
Same journal

Centromeric satellite expansion drives genome evolution in the snowy owl.

Genome biology·2026
Same journal

Mapping the landscape of allele-specific expression in porcine genomes.

Genome biology·2026
查看所有相关文章

相关实验视频

Updated: Feb 9, 2026

Author Spotlight: Advanced Techniques for Characterizing Tissue Mineralization in Bone Regeneration Research
07:29

Author Spotlight: Advanced Techniques for Characterizing Tissue Mineralization in Bone Regeneration Research

Published on: September 27, 2024

1.3K

PlasRAG:通过序列-文本对齐进行全面的等离子体表征和检索.

Yongxin Ji1, Jiaojiao Guan1, Herui Liao2

  • 1Department of Electrical Engineering, City University of Hong Kong, Kowloon, Hong Kong SAR (HKG), China.

Genome biology
|February 7, 2026
PubMed
概括
此摘要是机器生成的。

PlasRAG是一种用于表征等离子体的新工具,等离子体对于抗药性细菌的兴起至关重要. 它使用文本查询高效地检索等离子体DNA并分析它们的特性.

关键词:
生物医学语言模型多模式对比式学习检索增强生成 (RAG) 是一个.序列到文本等离子体特性表征.文本到序列等离子体检索

更多相关视频

Primer Extension Capture: Targeted Sequence Retrieval from Heavily Degraded DNA Sources
15:28

Primer Extension Capture: Targeted Sequence Retrieval from Heavily Degraded DNA Sources

Published on: September 3, 2009

20.8K
Optimization for Sequencing and Analysis of Degraded FFPE-RNA Samples
07:30

Optimization for Sequencing and Analysis of Degraded FFPE-RNA Samples

Published on: June 8, 2020

12.8K

相关实验视频

Last Updated: Feb 9, 2026

Author Spotlight: Advanced Techniques for Characterizing Tissue Mineralization in Bone Regeneration Research
07:29

Author Spotlight: Advanced Techniques for Characterizing Tissue Mineralization in Bone Regeneration Research

Published on: September 27, 2024

1.3K
Primer Extension Capture: Targeted Sequence Retrieval from Heavily Degraded DNA Sources
15:28

Primer Extension Capture: Targeted Sequence Retrieval from Heavily Degraded DNA Sources

Published on: September 3, 2009

20.8K
Optimization for Sequencing and Analysis of Degraded FFPE-RNA Samples
07:30

Optimization for Sequencing and Analysis of Degraded FFPE-RNA Samples

Published on: June 8, 2020

12.8K

科学领域:

  • 基因组学就是基因组学.
  • 生物信息学是一种生物信息学.
  • 微生物学 微生物学

背景情况:

  • 等离子体是多药耐药性和细菌致病性的关键驱动因素,存在重大临床问题.
  • 许多等离子体仍然没有注释,这阻碍了全面的理解和表征.
  • 需要有效的工具来分析等离子体属性并促进DNA检索.

研究的目的:

  • 介绍PlasRAG,一种用于等离子体表征和DNA检索的新型计算工具.
  • 开发一种方法来整合塑料的多面性质分析.
  • 为了实现基于文本查询的等离子体DNA检索.

主要方法:

  • PlasRAG使用双向多模式信息检索模型.
  • 该模型将DNA序列与文本数据对齐,以便进行增强分析.
  • 该工具集成了查询等离子体的全面属性表征.

主要成果:

  • 在等离子体属性表征方面,PlasRAG表现出强大的性能.
  • 该工具为等离子体DNA提供了增强的分析能力.
  • 实验验证证证了PlasRAG的建筑设计的有效性.

结论:

  • PlasRAG提供了一种有效的解决方案,用于对未注释的等离子体进行全面的表征.
  • 该工具通过整合序列和文本数据来推进等离子体分析.
  • PlasRAG解决了等离子体研究中传统方法的局限性.