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Updated: Feb 9, 2026

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单剂量PDGFB循环RNA可使持续的生长因子表达加速糖尿病伤口愈合

Yi-Qi Shen1, Yan Zhang1, Liu-Yi Yao1

  • 1Dermatology Hospital, Southern Medical University, Guangzhou, 510091, China.

Journal of nanobiotechnology
|February 7, 2026
PubMed
概括

一种新型的脂质纳米粒子 (LNP) 封装的循环RNA (circRNA) 传递血小板衍生生长因子-B (PDGFB) 有效治疗糖尿病足 (DFU). 这种单剂量治疗促进了持续的PDGFB表达,加速了伤口愈合和改善了组织修复.

关键词:
这是循环RNARNA.糖尿病伤口愈合的治疗方法脂质纳米颗粒的使用方法这是PDGFBB.一个单细胞RNAseqqq

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