低体重指数与重症患者的再输管之间的关系:一个多中心的回顾性队列研究
Toshinori Maezawa1,2, Masaaki Sakuraya3,4, Tadahiro Goto5
1Department of Emergency and Intensive Care Medicine, JA Hiroshima General Hospital, 1-3-3 Jigozen, Hatsukaichi, Hiroshima, 738-8503, Japan. toshinori.hds@gmail.com.
Journal of anesthesia, analgesia and critical care
|February 7, 2026
概括
在重症监护中的体重不足患者在机械通风后面临更高的再输管风险. 这项研究证实,较低的体重指数 (BMI) 是这种风险增加的重要因素.
科学领域:
- 关键护理医学 关键护理医学
- 肺部病理学 肺部病理学
- 临床营养学 临床营养学
背景情况:
- 在重症监护室 (ICU) 的体重不足患者由于生理储备减少,在医院内死亡的风险更高.
- 低体重指数 (BMI) 与机械通风患者的再输管风险之间的关联尚未得到充分证实.
研究的目的:
- 调查身体质量指数 (BMI) 与需要机械通风的成年患者的再输管风险之间的关系.
主要方法:
- 一项回顾性队列研究利用了2018-2023年日本重症监护患者数据库 (JIPAD) 的数据.
- 包括在内的成人患者接受机械通风 ≥24小时,再输管定义为机械通风在抽管后72小时内.
- 多变量逻辑回归分析了BMI类别 (体重不足,正常,超重,肥胖) 调整为已知的风险因素.
主要成果:
- 这项研究包括41016名患者;整体再输管率为5.9%.
- 体重不足的患者 (BMI <18.5 kg/m2) 的再灌输率最高 (8.4%) 和显著增加的风险 (aOR 1.58).
- 肥胖 (BMI ≥30.0 kg/m2) 与较低的再化风险 (aOR 0.69) 有关,这种关联在年龄分层分析中仍然存在.
结论:
- 较低的体重指数 (BMI) 与机械通风患者重新灌输风管的风险增加有关.
- 这一发现在不同年龄组中保持一致,突出显示BMI是评估再化风险的关键因素.
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