现场直播运动干预在怀孕妇女与MASLD (现场-MASLD):一个随机对照试验的协议
Mingyue Wang1,2, Yuying Wu1,2, Huimin Guan3
1Department of Maternal and Child Health, School of Public Health, Peking University/National Health Commission Key Laboratory of Reproductive Health, Beijing, PR China.
Annals of the New York Academy of Sciences
|February 8, 2026
概括
这项研究研究了一项针对代谢功能障碍相关的脂肪性肝病 (MASLD) 的孕妇的现场直播运动计划. 该干预措施旨在通过在怀孕期间减少肝脏脂肪来改善母亲和婴儿健康结果.
科学领域:
- 产科和妇科 产科和妇科
- 肝病学 肝病学是一种肝病学.
- 公共卫生 公共卫生
背景情况:
- 在生育年龄的妇女中,与代谢功能障碍相关的脂肪性肝病 (MASLD) 会增加妊娠并发症和不良妊娠结果的风险.
- 孕期MASLD可能会对后代的长期健康产生负面影响.
- 需要有效的干预措施来管理怀孕期间的MASLD.
研究的目的:
- 评估在被诊断患有MASLD的孕妇中直播运动干预措施的有效性.
- 评估干预对MASLD进展和母婴健康结果的影响.
- 为患有MASLD的孕妇提供临床管理策略的证据.
主要方法:
- 一个双臂随机对照试验 (Live-MASLD试验) 涉及第一 trimester中患有MASLD的孕妇.
- 干预组在第二和第三个三个月内接受监督,直播的炼计划.
- 对照组接受例行产前护理;包括分娩后在内的多个时间点进行评估.
主要成果:
- 主要结局:通过视觉暂时弹性图 (ViTE) 测量肝硬化指数 (LiSA) 的变化之间的组间差异.
- 二次结果包括各种母亲和婴儿健康指标.
- 包括健康经济评估的过程评估.
结论:
- 这项研究将提供关于直播运动对妊娠期MASLD的有效性的科学证据.
- 研究结果将为管理孕妇群体MASLD的临床指南提供信息.
- 这项干预有可能改善母婴健康轨迹.
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