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Updated: Feb 10, 2026

Interphase Fluorescence in situ Hybridization of Bone Marrow Smears of Multiple Myeloma
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针对PRKCN,一个重要的驱动器,在多发性骨髓瘤中独立于激酶活动,调节mTOR-IRF4轴

Koukou Tang1, Dongpeng Jiang1, Peng Ke2

  • 1Institute of Blood and Marrow Transplantation, National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, Collaborative Innovation Center of Hematology, The First Affiliated Hospital of Soochow University, Soochow University, Suzhou, Jiangsu, China.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
|February 8, 2026
PubMed
概括

蛋白激酶N (PKN) C是多发性骨髓瘤 (MM) 的新型治疗点. 向PKN C可以克服耐药性,并改善MM模型的结果.

关键词:
在 IRF4 基础上,IRF4 是一个 IRF4 项目.在 NF-κB 信号传输中.在mTOR信号传输中.多发性骨髓瘤是多发性骨髓瘤的一种.蛋白质激酶酶是一种蛋白质激酶.

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