通过皮肤进行的电神经刺激和阿片类药物止痛:探索潜在的协同作用关系
Chaoran Li1, Ruocheng Xu2, Yunjing Qiu3
1Department of Acupuncture and Moxibustion, The Third Affiliated Hospital of Zhejiang Chinese Medical University (Zhongshan Hospital of Zhejiang Province), Hangzhou, China; The Third School of Clinical Medicine (School of Rehabilitation Medicine), Zhejiang Chinese Medical University, Hangzhou, China; Key Laboratory of Acupuncture and Neurology of Zhejiang Province, Department of Neurobiology and Acupuncture Research, Zhejiang Chinese Medical University, Hangzhou, China.
通过皮肤进行的电神经刺激 (TENS) 与阿片类药物相结合,可以增强疼痛缓解,同时降低阿片类药物风险. 这种协同方法提供了一个有前途的多式联运战略,以改善患者的治疗结果,并尽量减少伤害.
科学领域:
- 疼痛管理 疼痛管理
- 神经科学是一个神经科学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 临床止痛治疗面临着平衡疼痛缓解与阿片类药物风险的挑战.
- 穿皮电神经刺激 (TENS) 是一种非药物,非侵入性疼痛缓解方法.
- TENS显示了与阿片类药物有协同效应的潜力.
研究的目的:
- 审查TENS与阿片类药物协同作用的证据.
- 为了分类TENS模式和参数.
- 检查TENS-阿片类药物组合的交互机制和优化策略.
主要方法:
- 对TENS和阿片类药物相互作用的现有文献进行系统审查.
- 不同的TENS参数和交付方法的分类.
- 对TENS-阿片类药物协同作用的拟议机制的分析.
主要成果:
- TENS-阿片类药物协同作用可以增强疼痛缓解和减少阿片类药物消费.
- 优化策略包括TENS早期应用和个性化的参数.
- 一个"TENS +低剂量阿片类药物"方案是一个有前途的多式联络方法.
结论:
- 将TENS与阿片类药物结合起来,为改善疼痛管理提供了一个可行的策略.
- 这种多模式的方法可以减少与阿片类药物相关的危害,并改善临床结果.
- 需要进一步的研究来确认协同作用和优化个性化疼痛药.
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