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Updated: May 4, 2026

Avidity-based Extracellular Interaction Screening AVEXIS for the Scalable Detection of Low-affinity Extracellular Receptor-Ligand Interactions
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通过使用SpyCatcher和SnoopCatcher配对的工程链分支双特定VHH复合体 ("Dendrobodies")

Kota Kurogane1, Miyuu Sekine2, Ryutaro Asano2

  • 1Graduate School of Science and Engineering, Yamagata University, 4-3-16 Jyonan, Yonezawa, Yamagata, 992-8510, Japan.

Biochemical and biophysical research communications
|February 8, 2026
PubMed
概括

一种新的Dendrobody架构克服了双特异抗体 (bsAbs) 的硬质障碍,增强了它们的治疗潜力. 这种设计可以通过引导免疫细胞向瘤进行有效的T细胞介导癌细胞杀死.

关键词:
癌症 癌症 癌症 癌症蛋白质的设计 蛋白质的设计蛋白质工程是一种蛋白质工程.

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