认知的氧气依赖:在西藏高地人的可逆认知变化背后的神经机制跨环境
Xiaoyan Li1, Hao Li2, Yaping Zeng3
1School of Education, Lanzhou City University, Lanzhou 730000, China; Plateau Brain Science Research Center, Tibet University, Lhasa 850000, China.
NeuroImage
|February 8, 2026
概括
高海拔低氧选择性地抑制西藏人的口头工作记忆,不会造成永久性损伤. 大脑功能适应性地重组以优化低氧情况下的能量,当氧气水平提高时恢复.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 人类的适应能力
背景情况:
- 西藏人群体表现出独特的生理适应能力,适应高海拔低氧.
- 这些适应的基础的神经认知机制,特别是关于工作记忆的,尚未完全理解.
研究的目的:
- 研究长期高海拔低氧对藏族原住民工作记忆的影响.
- 要区分适应性功能调整和不可逆转的神经功能障碍.
主要方法:
- 多模式方法包括行为测试,事件相关潜力 (ERP) 和时间频率分析.
- 高海拔地区的藏人,低海拔地区的藏人移民,以及低海拔地区的汉族人控制的比较.
主要成果:
- 藏族原住民的空间工作记忆没有受到影响.
- 在西藏本土人中,口头工作记忆的准确性下降,但随着居住在较低海拔地区的持续时间而恢复.
- 在高海拔原住民中,补偿神经活动 (增加LPP振幅和β频带功率) 在搬迁后显示出剂量依赖的下降.
结论:
- 高海拔低氧导致可逆的,能量优化驱动的口头工作记忆的适应性重组,而不是永久性损伤.
- 大脑的可塑性允许功能调整,以应对极端环境条件,如缺氧.
更多相关视频
16:23Automated, Quantitative Cognitive/Behavioral Screening of Mice: For Genetics, Pharmacology, Animal Cognition and Undergraduate Instruction
Published on: February 26, 2014
14.9K
13:20Online Repetitive Transcranial Magnetic Stimulation of Dorsomedial and Dorsolateral Prefrontal Cortex in Cognition Decision Making, and Cognitive Dissonance
Published on: December 5, 2025
994
相关概念视频
01:38Cognitive Dissonance
37.5K
Social psychologists have documented that feeling good about ourselves and maintaining positive self-esteem is a powerful motivator of human behavior (Tavris & Aronson, 2008). In the United States, members of the predominant culture typically think very highly of themselves and view themselves as good people who are above average on many desirable traits (Ehrlinger, Gilovich, & Ross, 2005). Often, our behavior, attitudes, and beliefs are affected when we experience a threat to our...
37.5K
01:27Language and Cognition
806
Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
806
01:25Cognitive Therapy
1.1K
Cognitive therapy, pioneered by Aaron T. Beck in the 1960s, is a structured approach to addressing psychological distress by focusing on the influence of thoughts on emotions and behaviors. All cognitive therapies involve the basic assumption that human beings have control over their feelings, and that how individuals feel about something depends on how they think about it. Unlike psychoanalytic methods that delve into unconscious processes or humanistic approaches emphasizing...
1.1K
01:23Cognition and Behavior
383
Social psychology examines the complex interplay between individual mental processes and social interactions. Historically, the field was divided into two domains: social behavior and social cognition. Researchers focusing on social behavior analyzed actions within social contexts, such as conformity, aggression, or cooperation. Meanwhile, social cognition researchers investigated how people perceive, interpret, and mentally represent their social environments. However, modern perspectives no...
383
01:21Cognitive Learning
1.2K
Cognitive learning is based on purposive behavior, incidental learning, and insight learning.
E. C. Tolman's theory of purposive behavior emphasizes that much behavior is goal-directed. He argued that to understand behavior, we must look at the entire sequence of actions leading to a goal. For instance, high school students study hard, not just due to past reinforcement but also to achieve the goal of getting into a good college.
Tolman introduced the idea that behavior is influenced by...
E. C. Tolman's theory of purposive behavior emphasizes that much behavior is goal-directed. He argued that to understand behavior, we must look at the entire sequence of actions leading to a goal. For instance, high school students study hard, not just due to past reinforcement but also to achieve the goal of getting into a good college.
Tolman introduced the idea that behavior is influenced by...
1.2K
01:20Introduction to Cognitive Psychology
2.5K
Cognitive psychology is the field of psychology dedicated to examining how people think. It attempts to explain how and why we think the way we do by studying the interactions among human thinking, emotion, creativity, language, and problem-solving, as well as other cognitive processes. Cognitive psychology studies how information is processed and manipulated in remembering, thinking, and knowing.
This field emerged in the mid-20th century, following a period dominated by behaviorism, which...
This field emerged in the mid-20th century, following a period dominated by behaviorism, which...
2.5K