心脏阶段对皮层-脊柱刺激性的影响:从输入-输出曲线的见解
Paolo Di Luzio1, Mauro Gianni Perrucci2, Francesca Ferri3
1Department of Psychology, University G. d'Annunzio Chieti-Pescara, 66100 Chieti, Italy; Department of Psychology, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, UK.
NeuroImage
|February 8, 2026
概括
心脏信号会影响大脑活动,在缩期间会受到更大的抑制. 了解心脑合可以提高大脑刺激的有效性和研究中的可重现性.
科学领域:
- 神经科学是一个神经科学.
- 心脏病学 心脏病学
- 生理学 生理学 生理学
背景情况:
- 内脏信号,特别是心脏振荡,显著影响皮质活动.
- 之前的研究表明心脏收缩 (心缩) 可能会抑制大脑活动,但与皮质刺激性的确切关系尚不清楚.
研究的目的:
- 为了研究心脏阶段和皮质脊髓刺激能力 (CSE) 之间的关系.
- 为了确定心脏输出变化如何影响运动唤起潜力 (MEP) 幅度.
主要方法:
- 结合电生理学措施与跨磁刺激 (TMS) 针对左侧运动皮层.
- 与心脏相对应的MEP的模拟输入-输出 (I/O) 曲线与心脏相对应的心脏相 (静心和腹心).
- 在与节拍间隔 (IBI) 相比,逐个试验评估了MEP幅度.
主要成果:
- 在缩期间,CSE表现出更大的抑制,由降低的MEP幅度和减少的皮质运动增益证明.
- MEP 振幅与心脏输出强度有负相关性,通过心跳间隔长度表示.
- 在缩期间观察到皮质运动增强的减少.
结论:
- 心脏信号积极调节大脑刺激能力,影响皮质脊髓通路.
- 考虑心脏周期可以提高TMS和电生理学研究中的可重现性.
- 临床应用包括优化非侵入性脑刺激和神经康复协议,以提高疗效和运动恢复.
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