相关实验视频

Updated: Feb 10, 2026

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions
13:56

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions

Published on: July 18, 2013

11.6K

细胞巨乳病毒 (CMV) 编码的直接早期1 (IE1) 蛋白质通过干扰宿主PML-DISC1相互作用来扰乱神经前体的增殖

Atsushi Saito1, Stephanie Tankou2, Kazuhiro Ishii2

  • 1Neuroscience,; Psychiatry.

The Journal of biological chemistry
|February 8, 2026
PubMed
概括

先天性细胞巨乳病毒 (CMV) 感染会损害神经前体的增殖. 使用CRISPR/Cas9准病毒IE1蛋白挽救了这个缺陷,揭示了先天性CMV大脑病理学的关键机制.

关键词:
这就是CRISPR/CasPR.在 DISC1 中.在PML中,PML是PML.大脑大脑大脑的大脑大脑一种先天性感染.细胞巨型病毒 (cytomegalovirus) 是一种病毒.神经前代子的神经前代子神经发育的神经发育病毒 病毒 病毒 病毒

更多相关视频

Neural-Colony Forming Cell Assay: An Assay To Discriminate Bona Fide Neural Stem Cells from Neural Progenitor Cells06:31

Neural-Colony Forming Cell Assay: An Assay To Discriminate Bona Fide Neural Stem Cells from Neural Progenitor Cells

Published on: March 6, 2011

22.6K
High-Throughput Transcriptome Analysis for Investigating Host-Pathogen Interactions14:58

High-Throughput Transcriptome Analysis for Investigating Host-Pathogen Interactions

Published on: March 5, 2022

4.8K

相关概念视频

siRNA - Small Interfering RNAs02:30

siRNA - Small Interfering RNAs

Small interfering RNAs, or siRNAs, are short regulatory RNA molecules that can silence genes post-transcriptionally, as well as the transcriptional level in some cases. siRNAs are important for protecting cells against viral infections and silencing transposable genetic elements.
In the cytoplasm, siRNA is processed from a double-stranded RNA, which comes from either endogenous DNA transcription or exogenous sources like a virus. This double-stranded RNA is then cleaved by the...
18.7K
Small interfering RNAs (siRNA)02:30

Small interfering RNAs (siRNA)

4.6K
Encoding01:19

Encoding

Information enters the brain through encoding, which is the input of information into the memory system. Once sensory information is received from the environment, the brain labels or codes it. The information is then organized with similar information and connected to existing concepts. Encoding occurs through automatic processing and effortful processing.
Automatic processing involves the encoding of details like time, space, frequency, and the meaning of words, usually done without conscious...
869
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
5.2K
Predator-Prey Interactions02:39

Predator-Prey Interactions

Predators consume prey for energy. Predators that acquire prey and prey that avoid predation both increase their chances of survival and reproduction (i.e., fitness). Routine predator-prey interactions elicit mutual adaptations that improve predator offenses, such as claws, teeth, and speed, as well as prey defenses, including crypsis, aposematism, and mimicry. Thus, predator-prey interactions resemble an evolutionary arms race.
21.7K
Factors Affecting Protein-Drug Binding: Drug Interactions01:23

Factors Affecting Protein-Drug Binding: Drug Interactions

Drug interactions are a critical aspect of pharmacology and can occur when two or more drugs compete for the same binding site. This competition can result in one drug displacing another, altering the effect of the displaced drug. Drug interactions are complex processes that rely heavily on how much of the displacer drug is present and how strongly it can bind to the same sites as the displaced drug.
Displacement interactions can have varying outcomes, ranging from toxicity to virtually...
611