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在DNA损伤下准EphA2会通过p21诱导导致线粒体绕道

Ayuka Nakamura1, Junna Tanaka1, Ryuzaburo Yuki1

  • 1Laboratory of Biochemistry & Molecular Biology, Kyoto Pharmaceutical University, Kyoto 607-8414, Japan.

The Journal of biological chemistry
|February 8, 2026
PubMed
概括

在DNA损伤后,EphA2 (Ephrin受体A2) 的上调促进癌细胞的生存,通过维持G2捕获. 抑制EphA2触发了p21依赖的线粒体旁路和四化,减少了增殖,并提供了一个治疗策略.

关键词:
亚德里亚胺氨酸是什么阿德里亚胺氨酸造成的DNA损伤是DNA损伤.在 EphA2 中.G2 - 逮捕G2 - 逮捕G2 - 逮捕

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