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Updated: Feb 10, 2026

Describing a Transcription Factor Dependent Regulation of the MicroRNA Transcriptome
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在HEK293细胞中调节ER居民转录因子NFE2L1

Maiko Yasui1, Izumi Nagae2, Ryoichi Murase1

  • 1Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan.

Biological & pharmaceutical bulletin
|February 8, 2026
PubMed
概括

核因子红色素衍生的2像1 (NFE2L1) 调节与CREB3/ATF6家族成员不同,与ER相关的降解 (ERAD) 因素如SEL1L/Hrd1显著影响其表达和稳定性. 这突显了内细胞网膜中多样化的N-糖化蛋白调节.

关键词:
细胞内膜网关联退化 (ERAD)基甲基谷氨基-CoA (HMG-CoA) 降解酶降解1 (Hrd1) 的降解核因子红色素衍生物2类似1 (NFE2L1)类似lin-12的抑制器/增强器 (SEL1L)含有瓦洛的蛋白质 (VCP)

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