参与者开始认为剂量过多的每日药物使用频率:通过电子药物笔记本使用个人健康记录基础设施的基于问卷的研究
Shungo Imai1, Masaki Asano1, Yuri Shimizu1
1Keio University Faculty of Pharmacy, 1-5-30 Shibakoen, Minato-ku, Tokyo 105-8512, Japan.
Biological & pharmaceutical bulletin
|February 8, 2026
概括
许多患者认为每天两次服用药物的剂量过多,这会影响药物坚持. 将药物计划简化为每天服用一次,可以提高患者的满意度和治疗效率.
科学领域:
- 药理学 药理学是指药理学的学科.
- 患者的坚持 患者的坚持
- 医疗保健服务研究 医疗服务研究
背景情况:
- 药物坚持是重要的临床挑战,经常受到频繁的剂量计划的负面影响.
- 虽然每天服用一次方案是最好的,但患者对过度剂量频率的看法需要进一步调查.
- 了解患者对剂量频率的偏好对于提高药物治疗满意度和优化药物治疗至关重要.
研究的目的:
- 为了确定特定的药物剂量频率,患者开始将其视为过度.
- 为了确定患者的特征和与药物相关的因素,与过量剂量的感知相关.
- 为简化药物治疗方案提供基于证据的建议.
主要方法:
- 在成年患者 (≥20岁) 中进行了基于网络的问卷调查,这些患者在90天内服用口服药物.
- 该调查利用了电子药物笔记本个人健康记录基础设施,并包括关于感知过度剂量的问题.
- 采用多变量逻辑回归分析来确定与过量剂量的感知相关的因素,控制混因素.
主要成果:
- 在1478名受访者中,有1236人被纳入分析,其中28.9%的人报告他们的药物使用频率过度.
- 与每日一次剂量相比,每天两次或更频繁的剂量与过度感知有显著的关联.
- 该研究确定了每天两次的剂量作为患者超越药物频率明显更有可能认为过度的门.
结论:
- 每天服用两次剂量代表了临界值,患者更有可能发现他们的药物频率过高.
- 将药物治疗方案简化为每天一次的剂量对于改善患者的坚持和满意度很重要.
- 这些发现强调了医疗保健提供者在处方和管理患者药物治疗时需要考虑剂量频率的必要性.
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