相关实验视频
Updated: Feb 10, 2026

06:10
Live Imaging of Mouse Secondary Palate Fusion
Published on: July 27, 2017
8.0K
人类胚胎和胎儿的二次 palatal 融合的时间
Puck Pauline Mulder1,2, Jess Johanna Peters2,3, Yousif Dawood1,2,4
1Department of Obstetrics and Gynecology, Amsterdam UMC Location University of Amsterdam, Amsterdam, the Netherlands.
Birth defects research
|February 8, 2026
概括
人类的二次口腔发育发生在卡内基阶段18-23之间,与CS23.23的架接触. 这一关键的窗口突出了怀孕早期对口腔形成药物暴露的风险.
科学领域:
- 发展生物学 发展生物学
- 人类胚胎学 人类胚胎学
- 遗传异常是一种先天性异常.
背景情况:
- 面部发育涉及门 derivatives; 干扰导致口唇/ palatal (CL/P) 的裂口.
- CL/P 影响饮食,言语和心理社会福祉.
- 了解二次口腔形成是CL/P病变发生的关键.
研究的目的:
- 评价人类二次口腔发育的时间和形态.
- 专注于胚胎 (卡内基阶段17-23) 和胎儿 (9-11周 PC).
主要方法:
- 组织学切口和微型CT扫描的分析.
- 研究人员检查了26个人类标本,涉及关键发育阶段.
主要成果:
- 在卡内基阶段18出现了口腔架子,垂直增长到CS22.
- 横向重定位和中间延伸发生在CS22.
- 在CS23观察到的货架接触 (融合开始),完成9周PC.
结论:
- 人类二次口腔发育的精细时间表.
- 确定了一个关键的发育窗口 (CS17-23).
- 建议重新评估在怀孕早期的药物管理指南,因为潜在的原性风险.
关键词:
裂唇和 (CL/P) 的情况组织学 组织学 组织学人类胚胎的人类胚胎人类胎儿人类胎儿微型计算机断层扫描 (微型CT)palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf palatal shelf二级宫殿的发展发展.相关概念视频
Development of the Sexual Organs in the Embryo and Fetus
3.8K
Development of the reproductive organs in an embryo starts from a bipotential state. This means the early embryo can develop either male or female reproductive organs. The formation of these organs begins with the growth of gonadal ridges that arise from the intermediate mesoderm during the fifth week of development.
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the...
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the...
3.8K
Nuclear Fusion
33.9K
The process of converting very light nuclei into heavier nuclei is also accompanied by the conversion of mass into large amounts of energy, a process called fusion. The principal source of energy in the sun is a net fusion reaction in which four hydrogen nuclei fuse and ultimately produce one helium nucleus and two positrons.
A helium nucleus has a mass that is 0.7% less than that of four hydrogen nuclei; this lost mass is converted into energy during the fusion. This reaction produces about...
A helium nucleus has a mass that is 0.7% less than that of four hydrogen nuclei; this lost mass is converted into energy during the fusion. This reaction produces about...
33.9K
Secondary Active Transport
138.1K
One example of how cells use the energy contained in electrochemical gradients is demonstrated by glucose transport into cells. The ion vital to this process is sodium (Na+), which is typically present in higher concentrations extracellularly than in the cytosol. Such a concentration difference is due, in part, to the action of an enzyme “pump” embedded in the cellular membrane that actively expels Na+ from a cell. Importantly, as this pump contributes to the high concentration of...
138.1K
Secondary Active Transport
9.7K
One example of how cells use the energy contained in electrochemical gradients is demonstrated by glucose transport into cells. The ion vital to this process is sodium (Na+), which is typically present in higher concentrations extracellularly than in the cytosol. Such a concentration difference is due, in part, to the action of an enzyme "pump" embedded in the cellular membrane that actively expels Na+ from a cell. Importantly, as this pump contributes to the high concentration of...
9.7K
Secondary Healthcare System
2.1K
Secondary healthcare is offered by a specialist, generally in hospitals or clinics for patients referred by primary healthcare providers. It occurs when a person has an illness or injury that requires specific medical care. Secondary care is often referred to as acute care. Secondary care can range from uncomplicated care to repair a minor laceration or treat a strep throat infection to more complicated emergent care, such as treating a head injury sustained in an automobile accident. Whatever...
2.1K
Primary and Secondary Growth in Roots and Shoots
60.6K
Vascular plants, which account for over 90% of the Earth’s vegetation, all undergo primary growth—which lengthens roots and shoots. Many land plants, notably woody plants, also undergo secondary growth—which thickens roots and shoots.
60.6K

