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Updated: Feb 10, 2026

Genome Engineering of Primary Human B Cells Using CRISPR/Cas9
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SETDB1/ATF7IP调节了HUSH调节基因的精确基因工程

Brian L Ruis1, Henry Ward2, Chad L Myers2

  • 1Department of Medicine, University of Virginia Medical School, 6222 Pinn Hall, 1307 Lane Rd., VA, 22903, Charlottesville, USA.

Epigenetics & chromatin
|February 8, 2026
PubMed
概括

像SETDB1/ATF7IP和HUSH这样的染色质修饰剂调节精确基因组编辑 (PGE) 途径. 了解这些调节器可以提高PGE的效率,特别是对于转基因.

关键词:
在ATF7IP中使用.基因编辑 基因编辑H3K9me3是什么意思 H3K9me3是什么意思胡什 (Hush) 是一种汉语.在SETDB1中,我们可以使用SETDB1.这就是SSDI的意义.

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