从脑内神经记录中解读幻肢运动
Cecilia Rossi1, Marko Bumbasirevic2, Paul Čvančara3
1Institute of Neuroinformatics, University of Zurich and ETH Zurich, Zurich, Switzerland.
Nature communications
|February 8, 2026
概括
坐骨神经中的内神经电极通过解码截肢者的幻肢运动来实现假体控制. 这种方法对先进的双向神经假体有很大的前景.
科学领域:
- 神经科学是一个神经科学.
- 生物医学工程 生物医学工程
- 假肢 假肢是一种假肢.
背景情况:
- 肢体损失导致感觉运动缺陷,往往需要假肢装置.
- 直接神经记录用于假肢控制面临诸如低信号幅度和神经接口困难等挑战.
研究的目的:
- 为了研究肌内多通道电极,以获取移骨截肢患者的运动信号.
- 解码自发的幻肢运动,以进行先进的假肢控制.
主要方法:
- 植入横向肌内多通道电极在两个移骨截肢者的远距离坐骨神经分支中.
- 记录与幻膝盖,脚和脚运动相关的多单元活动.
- 使用基于尖端神经网络 (SNN) 的解码器进行运动预测.
主要成果:
- 确定了与幻肢运动相对应的关节和方向特定的神经活动.
- 在预测试图移动方面,SNN解码器超过了传统方法.
- 内神经和肌肉间信号的整合进一步提高了解码精度.
结论:
- 来自坐骨神经的内神经记录可以解码幻肢运动.
- 这项技术支持开发双向的神经控制的假肢系统.
- 观察到神经内运动和感觉图的早期分离.
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