透皮活检和1期癌复发风险:一种倾向性得分匹配的队列研究
Jun Hyeok Yoo1, Maisy Song1, Joung Won Sung1
1Department of Urology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.
Annals of surgical oncology
|February 8, 2026
概括
针对T1细胞癌 (RCC) 的手术前脏质量活检 (RMB) 不会增加复发或升级风险. 这项研究支持人民币人民币.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 腎臟病學 (nephrology) 是一種醫學.
背景情况:
- 小瘤的发病率越来越高,需要安全的诊断方法.
- 通过皮肤进行质活检 (RMB) 的采用受到瘤安全问题的限制.
- 缺乏长期结果数据阻碍了人民币的常规使用.
研究的目的:
- 评估手术前RMB对cT1细胞癌 (RCC) 患者的升级和复发的影响.
- 在接受绝对手术的患者中评估RMB的瘤安全性.
- 提供长期结果数据,以告知临床对人民币的犹.
主要方法:
- 追溯队列研究将386名手术前RMB患者与772名倾向性得分匹配的对照人进行比较.
- 使用卡普兰-梅尔和考克斯回归的无复发生存 (RFS) 分析.
- 通过多变量逻辑回归来评估围脂肪侵袭的升级阶段.
主要成果:
- 在人民币和对照组之间的5年RFS没有统计学上显著的差异 (96.7%对比97.8%,p = 0.35).
- 人民币没有与复发率增加 (HR = 0.71,p = 0.35) 或升级阶段 (OR = 1.64,p = 0.182) 相关.
- 复发的独立预测因素包括瘤大小,核等级,高脏测量E分数和围脂肪入侵.
结论:
- 在T1 RCC中进行手术前的RMB与不良瘤结果无关.
- 这些发现证实了RMB对T1细胞癌的安全性.
- 支持人民币在小体管理规划中的实用性.
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