在内血管治疗期间出现的动脉支架,用于隔离的宫内动脉封闭
Christoph Riegler1,2, João Pedro Marto3,4, Pimrapat Gebert5,6
1Department of Neurology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Germany.
Journal of stroke
|February 9, 2026
概括
在静脉内治疗 (EVT) 期间为隔离的部内动脉封闭而进行的突发性动脉支架 (CAS) 改善了血管通透性,但在三个月后没有改善功能结果.
科学领域:
- 神经学 神经学
- 干预心脏病学 干预心脏病学
- 血管外科 血管外科
背景情况:
- 缺血性中风患者与隔离的宫内动脉封闭 (c-ICA-O) 可以从内血管治疗 (EVT) 获益,以改善大脑输液.
- 内血管治疗 (EVT) 经常与动脉支架 (CAS) 结合,以保持这些患者的血管通透性.
研究的目的:
- 在内血管治疗 (EVT) 期间评估新兴动脉支架 (CAS) 的疗效和安全性,用于隔离的宫内动脉封闭 (c-ICA-O).
主要方法:
- 一项涉及42个中心的回顾性跨国队列研究.
- 在症状发作后24小时内,比较了接受紧急CAS的患者和没有接受CAS的患者的结局.
- 共同初级结局包括24小时后c-ICA血管通透性和症状性内出血 (sICH);二级结局包括任何内出血 (ICH) 和3个月的残疾 (修改的兰金表).
主要成果:
- 在317名患者中,69.1%接受了CAS. 在24小时内,CAS组的血管通透率显著更高 (83.5%与40.7%相比).
- 症状性内出血 (sICH) 的发生率在两组之间是相似的 (2.3%对3.1%).
- 任何内出血 (ICH) 在CAS (19.3%对9.3%) 后更为常见,但CAS与3个月后的Rankin尺度得分没有变化.
结论:
- 对于孤立的c-ICA-O,在EVT期间出现的CAS在技术上是有效的,并且相当安全.
- 虽然CAS增加了血管通透性,但这并没有转化为中风后三个月的功能改善.
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