酒精使用患者的第三腹腔体积和心理测量变化
Jenna Lee1,2, Michelle A Patriquin3, Ramiro Salas1,4,5,6
1The Menninger Clinic, Houston, Texas, USA.
The American journal on addictions
|February 9, 2026
概括
酒精使用障碍 (AUD) 与大脑中第三室体积扩大有关. 这种大脑变化与AUD患者的普遍焦虑症状相关.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 放射学 放射学是一门学科.
背景情况:
- 酒精使用障碍 (AUD) 是一种具有神经学影响的严重精神疾病.
- 以前的研究表明AUD和大脑生物标志物之间存在联系,但皮质下体积变化及其临床相关性仍然不清楚.
- 了解酒精对大脑结构的影响对于AUD治疗至关重要.
研究的目的:
- 为了比较AUD和健康对照 (HC) 个体之间的皮层下大脑体积.
- 研究AUD患者改变的大脑体积和临床结果之间的关系.
- 阐明酒精消费如何影响特定的大脑区域.
主要方法:
- 71名被诊断患有AUD (DSM-IV标准) 的患者被招募并与71名HC匹配.
- 分析了40个双边皮下结构的体积在不同组之间的差异.
- 评估了皮下大脑体积变化与常见的精神病并发症之间的关联.
主要成果:
- 与HC相比,在AUD患者中观察到第三心室体积的显著增加.
- 在AUD组中,第三腹腔体积扩大和通用焦虑严重程度之间发现了积极的相关性.
- 这些发现突出了AUD中的特定结构性大脑变化.
结论:
- 该研究在AUD患者中发现了显著的第三腹腔扩大.
- 这种扩大与普遍焦虑有关,表明大脑结构和心理症状之间存在联系.
- 这项研究是首次报告与AUD临床结果相关的体积变化,强调了这种疾病中复杂的脑行为关系.
相关概念视频
01:30Alterations in Respiration II
1.9K
There are numerous types of normal and abnormal respiration. Based on ventilatory movements, breathing patterns are classified as regular, deep, or shallow. Examples include Biot's breathing, Cheyne-Stokes respiration, Kussmaul's breathing, hyperventilation, and hypoventilation. Each pattern is clinically significant and aids in evaluating patients.
In Biot's breathing, the respiratory rate and depth are irregular, alternating between periods of deep gasping and apnea. Common causes...
In Biot's breathing, the respiratory rate and depth are irregular, alternating between periods of deep gasping and apnea. Common causes...
1.9K
01:18Anatomy of the Brain: Ventricles
9.1K
There are hollow fluid-filled cavities known as ventricles deep inside the human brain. There are two lateral ventricles, one in each cerebral hemisphere, and each has three different projections — the anterior, inferior, and posterior horns visible from the lateral side. A thin membrane called the septum pellucidum separates the two lateral ventricles. The slender third ventricle in the diencephalon is connected to each lateral ventricle via a channel called the interventricular foramen.
9.1K
01:06Altered States of Awareness
1.2K
Altered states of consciousness represent significant deviations from one's normal mental state. These deviations can range from subtle changes in awareness to profound transformations in perception, thought processes, and sensory experiences. Altered states of consciousness can be triggered by various factors, including drug use, meditation, hypnosis, illness, or even intense fatigue.
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...
The ingestion of substances like stimulants or hallucinogens leads to chemical alterations in the brain...
1.2K
02:37Oxidation of Alcohols
16.2K
In this lesson, the oxidation of alcohols is discussed in depth. The various reagents used for oxidation of primary and secondary alcohols are detailed, and their mechanism of action is provided.
The process of oxidation in a chemical reaction is observed in any of the three forms:
The process of oxidation in a chemical reaction is observed in any of the three forms:
16.2K
01:30Alterations in Blood Pressure
2.2K
Alterations in blood pressure, such as hypertension (high blood pressure) and hypotension (low blood pressure), significantly affect human health. Understanding these conditions' classifications, causes, and symptoms is essential for effective management and treatment.
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart...
2.2K
02:29Ethers from Alcohols: Alcohol Dehydration and Williamson Ether Synthesis
13.0K
Overview
Ethers can be prepared from organic compounds by various methods. Some of them are discussed below,
Preparation of Ethers by Alcohol Dehydration
In this method, in the presence of protic acids, alcohol dehydrates to produce alkenes and ethers under different conditions. For example, in the presence of sulphuric acid, dehydration of ethanol at 413 K yields ethoxyethane, whereas it yields ethene at 443 K.
Ethers can be prepared from organic compounds by various methods. Some of them are discussed below,
Preparation of Ethers by Alcohol Dehydration
In this method, in the presence of protic acids, alcohol dehydrates to produce alkenes and ethers under different conditions. For example, in the presence of sulphuric acid, dehydration of ethanol at 413 K yields ethoxyethane, whereas it yields ethene at 443 K.
13.0K