运动能力和呼吸系统反应在早产,带有和没有支气管肺发育不良的儿童
Eleana Kouroukli1, Kosmas Sarafidis2, John Tsanakas1
1Pediatric Pulmonology and Cystic Fibrosis Unit, 3rd Department of Paediatrics, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Pediatric pulmonology
|February 9, 2026
概括
患有支气管肺功能障碍 (BPD) 的儿童表现出正常的肺功能,但在炼期间运动能力降低,呼吸系统效率受损. 这会影响他们早产后的长期呼吸系统健康.
科学领域:
- 儿科肺病学 儿科肺病学
- 呼吸系统医学 呼吸系统医学
- 运动生理学 运动生理学
背景情况:
- 支气管肺功能障碍症 (BPD) 是早产的常见并发症,导致慢性呼吸系统问题.
- 了解BPD对肺功能和运动的长期影响对于受影响的儿童至关重要.
研究的目的:
- 评估学龄儿童的肺功能和运动能力,这些儿童有过早生和/或BPD的病史.
- 为了比较患有BPD的儿童,没有BPD的早产儿童和健康对照儿童之间的努力呼吸模式和通风/气交反应.
主要方法:
- 一项前性观察性研究涉及三个组:早产患有BPD,早产无BPD,以及健康的出生后对照.
- 参与者接受了螺旋测量和心肺运动测试 (CPET),以评估肺功能和运动表现.
主要成果:
- 虽然精神测量 (FVC,FEV1,FEF25-75%,FEV1/FVC) 在所有组中都是可比的,但与对照组相比,BPD组的峰值氧气消耗 (V̇O2峰值%) 降低了.
- 在BPD组,二氧化碳 (VE/VCO2) 的通风器等价值显著增加,这表明在运动期间通风器效率下降.
- 在调整高度时,大多数CPET参数没有观察到显著差异,除了VE/VCO2.
结论:
- 患有BPD的儿童保持通过螺旋计测量正常的肺功能.
- 然而,他们在体力炼期间体验到运动能力降低和呼吸器效率下降.
- 这些发现凸显了BPD对呼吸系统健康和体力表现的持续影响,直到童年.
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