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Updated: Feb 10, 2026

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针对IAHSP的MK4重新定位:通过在中提炼和在玻璃中验证克服在vivo中的数据差距

Matteo Rossi Sebastiano1, Antonio Vicidomini2, Serena Francisco1

  • 1University of Torino, Molecular Biotechnology and Health Sciences Department, Turin 10126, Italy.

ACS chemical neuroscience
|February 9, 2026
PubMed
概括

梅纳特 (MK4) 通过纠正突变ALSIN蛋白功能,在治疗婴儿发作的上升性遗传性性 (IAHSP) 中表现有前途. 这项研究验证了MK4的有效性.

关键词:
阿尔辛 (Alsin) 是一种药物.在IAHSP中,IAHSP是在MK4MK4MK4MK4M药物重用是为了改变药物的用途.纤维细胞的细胞.线粒体中的线粒体.

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