在局部奶油配方中,Ganoderma lucidum (Reishi) 提取物的化品潜力
Sibel Dikmen Kucuk1, Paul Jabet2, Anthony Groso2
1Coordination Office of Specialization in Environment and Health Technologies, University of Düzce, Düzce, Turkey.
International journal of cosmetic science
|February 9, 2026
概括
从子废物中结干燥的雷希提取物显示出强大的抗氧化剂和铁酶抑制作用,使其成为一种安全,稳定的化品成分,用于抗衰老和增亮皮肤. 配方奶油符合所有安全性和稳定性标准.
科学领域:
- 化品科学 化品科学
- 自然产品化学 自然产品化学
- 皮肤病学 皮肤病学
背景情况:
- 化品行业正在寻找用于抗衰老和增亮皮肤的新奇天然成分.
- 从农业废物中提取的Ganoderma lucidum (Reishi) 提取物是生物活性化合物的潜在来源.
- 现有的化品活性剂,如阿吉瑞林和α-arbutin,在安全性和有效性方面存在局限性.
研究的目的:
- 为了评估雷希提取物的生物活性 (抗氧化剂,铁酶抑制,细胞毒性).
- 为了比较Reishi提取物与已确定的化品活性物质的特性.
- 开发和评估含有雷提取物的局部奶油配方的安全性和稳定性.
主要方法:
- 抗氧化能力通过铜 (II) 基试验进行评估.
- 使用从MNT-1细胞中测量的人类铁酶的铁酶抑制.
- 细胞毒性和安全剂量通过AlamarBlue®测定在HaCaT角质细胞中确定.
- 奶油配方通过多相乳化开发;物理化学,微生物安全性,防腐剂有效性和稳定性测试.
主要成果:
- 瑞芝提取物表现出显著的抗氧化活性 (861μmol TE/g) 和30%的铁酶抑制.
- 瑞士提取物表现出比阿吉瑞林和α-arbutin更大的安全差距.
- 配方奶油在物理上稳定,与皮肤相容 (pH),微生物学上安全,并在防腐剂有效性测试中有效.
结论:
- 蕾提取物是一种安全,稳定和生物活性的天然成分,具有用于化品应用的潜力.
- 它的抗氧化和铁酶抑制特性支持其在抗衰老和皮肤亮化配方中的使用.
- 开发的奶油配方证明了雷石提取物在护肤产品中的实际应用.
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