miRNA-biogenesis-defective

Anne-Sophie Chong1,2, Carla Roca1,3, Paula Morales-Sánchez3

  • 1Program in Molecular Mechanisms and Experimental Therapy in Oncology (Oncobell), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain.

JCI insight
|February 9, 2026
PubMed
概括

在DICER1和DGCR8微处理器中的遗传变化驱动甲状腺瘤的进展. 恶性转变涉及特定的遗传积累和miRNA下调,具有明显的微环境影响.

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