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Updated: Feb 10, 2026

Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity
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选择性SIK2/SIK3抑制重新编程髓状细胞中的亲和抗炎途径,改善自身免疫性疾病的结果

Steve De Vos1, Nicolas Desroy2, Susan J Bellaire3

  • 1Galapagos NV, Mechelen, Belgium.

JCI insight
|February 9, 2026
PubMed
概括

选择性抑制盐诱导性激酶2和3 (SIK2 / SIK3) 重编程髓状细胞,将它们从促炎型转变为调节性表型. 这种方法对治疗慢性炎症性自身免疫性疾病充满希望.

关键词:
自身免疫性疾病是一种自身免疫性疾病.这是一种自身免疫力.临床试验中的临床试验.皮肤病学 皮肤病学胃肠病学 胃肠病学鼠标模型 鼠标模型

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Selecting and Isolating Colonies of Human Induced Pluripotent Stem Cells Reprogrammed from Adult Fibroblasts13:23

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