相关实验视频
Updated: Feb 10, 2026

05:51
A Bright NIR-II Fluorescence Probe for Vascular and Tumor Imaging
Published on: March 17, 2023
2.3K
一个库马林功能化的NIR光探头,基于皮龙骨架,用于检测Cys及其应用
Huan Zhang1, Baoze Guo1, Junqing Zhou1
1Tianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, School of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin 300384, P. R. China. youlai@tjut.edu.cn.
Analytical methods : advancing methods and applications
|February 9, 2026
概括
一个新的基于蒂奥皮龙的光探针提供了对氨酸的敏感和快速检测. 这种工具对生物成像和各种样本的方便的基于手机的分析非常有希望.
科学领域:
- 生物化学 生物化学
- 分子生物学分子生物学
- 化学传感器 化学传感器
背景情况:
- 半素光探针对于敏感的半素检测至关重要.
- 目前的应用范围包括疾病监测,氧化还原平衡和药物毒性研究.
研究的目的:
- 设计和描述一种用于检测氨酸的新型光探针.
- 评估其在生物系统和现实世界样本中的性能.
主要方法:
- 开发一种基于蒂奥皮龙的光探针.
- 光物理性质的表征 (灵敏度,响应时间,选择性).
- 在细胞系 (RAW 264.7),斑马鱼和实际样本中进行应用测试.
主要成果:
- 探测器表现出很大的斯托克斯转移 (217 nm) 和高灵敏度 (13.60 nM).
- 它表现出快速响应时间 (3.0分钟),高稳定性和选择性.
- 在细胞成像,体内研究和样本分析中成功应用.
结论:
- 这种新型的光探针对于敏感和选择性氨酸检测是有效的.
- 它的实用性在生物模型和实践样本分析中得到了验证.
- 使用手机软件进行方便的氨酸水平测试的潜力.
相关概念视频
Carbon Skeletons
115.4K
Life on Earth is carbon-based, as all macromolecules that make up living organisms contain carbon atoms. All organic compounds have a carbon backbone. Each carbon atom is tetravalent and can bond with four other atoms, making it an extraordinarily flexible component of biological molecules. Because carbon’s valence electrons are stable, it rarely becomes an ion. As the carbon chain increases in length, structural modifications such as ring structures, double bonds, and branching side...
115.4K
Skeleton and Calcium Homeostasis
6.0K
Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
6.0K
Overview of the Axial Skeleton
9.5K
The skeleton is subdivided into two major divisions—the axial skeleton and the appendicular skeleton. The axial skeleton forms the vertical, central axis of the body. It includes all of the bones of the head, neck, chest, and back. It protects the brain, spinal cord, heart, and lungs. It also serves as the attachment site for muscles that move the head, neck, and back and for muscles that act across the shoulder and hip joints to move their corresponding limbs.
The axial skeleton of the...
The axial skeleton of the...
9.5K
Changes in the Appendicular Skeleton with Age
3.6K
The upper and lower limb initially develops as a small bulge called a limb bud, which appears on the lateral side of the early embryo. The upper limb bud appears near the end of the fourth week of development, with the lower limb bud appearing shortly after.
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
3.6K
Exponential Functions with Base e
261
Exponential functions with base e are essential for modeling continuous processes of growth and decay. The constant e, approximately 2.718, naturally arises in systems where change occurs proportionally to the current value. A positive exponent represents continuous growth, while a negative exponent represents continuous decay. These functions are especially useful for describing situations where change happens smoothly over time rather than in discrete steps.One clear example of exponential...
261
Applications of Integration to Probability Density Functions
71
Continuous probability distributions are used to model random variables that can take on any real value within a specified range. These variables do not take on isolated or countable values but rather exist on a continuum. For example, the height of an individual can be measured with increasing precision—such as 163.5 or 165.25 centimeters—demonstrating that height is a continuous random variable.The behavior of such variables is described using a probability density function (PDF),...
71

