根据表型和内型对过敏性鼻炎的个性化诊断和治疗的当前见解
Yue Gu1, Long-Lan Shu1, Tao Lu1
1Department of Otorhinolaryngology Upper Airway Inflammation and Tumor Laboratory, The First Affiliated Hospital of Chongqing Medical University Chongqing China.
World journal of otorhinolaryngology - head and neck surgery
|February 9, 2026
概括
过敏性鼻炎 (AR) 治疗需要通过了解其表型和内型来改进. 本综述探讨了这些分类,以更好地个性化患者管理.
科学领域:
- 免疫学 免疫学 免疫学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 过敏学 过敏学
背景情况:
- 过敏性鼻炎 (AR) 是一种由过敏原敏感和炎症媒介驱动的慢性鼻炎.
- 目前的AR治疗提供了症状缓解,但往往无法全面解决潜在机制.
- 在将AR的复杂机制与其多样化的临床表现联系起来时存在差距.
研究的目的:
- 审查有关AR表型和内型的最新发现.
- 为了澄清AR内型和表型之间的关联.
- 以指导基于这些分类的个性化AR治疗策略.
主要方法:
- 关于过敏性鼻炎的最新研究的文献综述.
- 根据表型和内型对AR进行分类的研究分析.
- 综合数据将内型与临床表现联系起来.
主要成果:
- 已经确定了不同的AR表型和内型.
- 具体的内型-表型关联正在出现.
- 这些分类为向治疗提供了一个框架.
结论:
- 了解AR表型和内型对于有效治疗至关重要.
- 在AR中,个性化医疗方法需要内型-表型相关性.
- 本综述为AR患者的早期识别和量身定制的管理提供了见解.
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