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Updated: Feb 10, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
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Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas

Published on: February 28, 2019

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氨酸轴转录组学定义了三种神经母细胞瘤亚型和一个固定的四基因预后特征,与免疫相关

Ying Zheng1, Yanan Zhang2, Xin Li3

  • 1Department of Anesthesiology, Tianjin Medical University Cancer Institute & Hospital, National Clinical Research Center for Cancer, Tianjin's Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China.

Translational pediatrics
|February 9, 2026
PubMed
概括

这项研究确定了基于氨酸-氨酸代谢的三种神经母细胞瘤 (NB) 亚型,开发了风险分层的四个基因签名,并预测了免疫治疗反应. 这些发现支持以代谢为基础的NB风险评估.

关键词:
神经母细胞瘤 (NB) 是一个氨酸代谢 (Arg代谢) 的代谢达成共识的聚类聚类.预后签名 预测签名瘤微环境是一个微环境.

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