病例报告:血管免疫原性T细胞淋巴瘤最初被诊断为带有多炎的eosinophilic粒状瘤
Yingmeng Ni1,2, Yidan Sun1,2, Simin Xie1,2
1Department of Pulmonary and Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Frontiers in medicine
|February 9, 2026
概括
血管免疫原性T细胞淋巴瘤 (AITL) 可以模仿聚炎 (EGPA) 带来的Eosinophilic granulomatosis,导致误诊. 在耐火EGPA病例中早期考虑淋巴瘤对于准确的诊断和治疗至关重要.
科学领域:
- 在瘤学瘤学.
- 免疫学 免疫学 免疫学
- 肺部病理学 肺部病理学
背景情况:
- 带有多胞膜炎 (EGPA) 的埃索诺菲尔粒状瘤和血管免疫原性T细胞淋巴瘤 (AITL) 具有重叠的临床特征.
- 这种重叠带来了重大的诊断挑战,可能导致误诊.
研究的目的:
- 要突出一个案例,AITL最初被误诊为EGPA.
- 强调在耐火EGPA呈现中考虑淋巴瘤的重要性.
主要方法:
- 研究了一名55岁的男性患者,其症状暗示EGPA.
- 诊断程序包括细针和手术淋巴结活检,流细胞计和分子检测.
- 对EGPA疗法和随后的化疗的治疗反应进行了监测.
主要成果:
- 最初对EGPA的诊断是耐标准治疗的.
- 手术淋巴结活检证实了具有特定T细胞标记物和EBV检测的AITL.
- CHOP化学疗法导致症状改善和异性腺素的正常化.
结论:
- AITL可能表现出模仿EGPA的特征,包括喘,阴道酸和鼻炎.
- 在非典型或耐火EGPA病例中,对淋巴细胞恶性瘤的高度怀疑指数是必要的.
- 适当的组织活检对于确定确诊和适当管理这些复杂病例至关重要.
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