格雷尤 (GRAYU):基于图形的数据库,整合了阿育吠陀配方,药用植物,植物化学品和疾病
Sarthak Joshi1, Aditi Pathak1, Dheemanth Reddy Regati1
1National Centre for Biological Sciences (TIFR), Bangalore, Karnataka, India.
Frontiers in pharmacology
|February 9, 2026
概括
我们开发了GRAYU,这是一个数据库,将印度传统医学,植物和疾病联系起来. 该资源有助于研究人员通过分析传统阿育吠陀配方的复杂生物关联来发现新的治疗假设.
科学领域:
- 药理学 药理学是指药理学的学科.
- 生物信息学是一种生物信息学.
- 民族医学 民族医学
背景情况:
- 传统印度医学拥有广泛的治疗知识,但缺乏现代药物发现的系统框架.
- 关于药用植物和配方的现有数据通常是无结构的,阻碍了计算分析.
研究的目的:
- 介绍GRAYU,一个综合传统印度药用植物知识的全面在线数据库.
- 通过连接配方,植物,植物化学品和疾病来促进系统的药物发现.
主要方法:
- 从多个类别的数据编辑和整合到一个单一的数据库中.
- 建立了1039种传统配方,12743种土著植物,129542种植物化学物质和13480种疾病之间的联系.
主要成果:
- 确定了超过130万种植物植物化学物质和116,000种植物疾病的关联.
- 揭示了重要的植物配方和配方疾病联系.
- 证明了GRAYU在分析植物化学类似物,植物替代和疾病网络方面的实用性.
结论:
- 格雷尤提供了一个用户友好的平台,可以探索传统的印度医学知识.
- 该数据库通过分析复杂的生物关联来支持新疗法的假设生成.
- 所有发现都需要对机械因果关系和生物活性进行实验验证.
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