在战场和战场之外暴露于多环芳化合物:对环境和人类健康的影响
Markis' D Hamilton1, Ritu Chauhan2, Anthony E Archibong3
1Department of Biomedical Sciences, School of Graduate Studies, Meharry Medical College, Nashville, TN, USA.
Toxicology reports
|February 9, 2026
概括
军事人员在战斗期间面临多环芳 (PAH) 暴露,导致癌症和器官功能障碍等潜在的健康问题. 暴露体方法为退伍军人监测和治疗策略提供了希望.
科学领域:
- 环境健康 环境健康
- 职业医学 职业医学 职业医学
- 毒理学 毒理学 毒理学
背景情况:
- 多环芳 (PAH) 是普遍存在的自然和人为来源的燃烧污染物.
- 军事人员在驻军和作战部署期间都暴露于PAHs.
- 部署期间低水平的PAH暴露可能导致服务人员和退伍军人的长期健康后果.
研究的目的:
- 审查PAHs在现役军事人员和退伍军人的暴露途径和不良健康影响.
- 确定与战斗相关的特定来源,有助于PAH暴露.
- 探索使用暴露体方法的潜在监测和治疗策略.
主要方法:
- 对科学文献进行了全面的范围审查.
- 搜索了五个数据库,寻找有关PAH暴露和退伍军人健康的研究.
- 从超过5万份初始出版物中确定了296项相关研究.
主要成果:
- 战斗环境通过爆炸,火灾和废物焚烧 (例如燃烧坑) 释放PAH.
- 在"沙漠盾牌"",沙漠风暴"和"持久自由"行动期间发生了显著的暴露.
- 气污染影响了人员,环境和海洋生态系统.
- 健康影响包括肺部,脏和生殖系统问题,以及增加癌症风险,通常与海湾战争综合征有关.
- 结合omics生物标志物和可穿戴监视器的Exposome方法显示出对特征暴露和告知治疗的希望.
结论:
- 战斗部署对军事人员造成PAH暴露的重大风险.
- 由PAH引起的健康问题对退伍军人来说是一个严重的问题.
- 暴露组框架为军事人群提供了一种全面的暴露评估和个性化的健康策略的新方法.
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