印度胆结石疾病的患病率:基于社区的横截面研究的见解
Shravani Umesh Mohite1,2, Nandkumar Panse3, Ravi Kannan4
1Division of Molecular Epidemiology and Population Genomics, Center for Cancer Epidemiology, Navi Mumbai, India.
BMJ public health
|February 9, 2026
概括
胆结石疾病的患病率在印度各地有很大差异,与胆囊癌相关的地区的患病率更高. 这凸显了针对胆结石的原因进行有针对性的监测和研究的需要.
科学领域:
- 胃肠病学 胃肠病学
- 流行病学 流行病学
- 在瘤学瘤学.
背景情况:
- 胆结石病 (GSD) 是常见的,与胆囊癌 (GBC) 有关.
- 印度显示GSD负担的区域差异,高风险和低风险GBC地区的数据有限.
- 了解GSD的流行对于公共卫生战略至关重要.
研究的目的:
- 调查印度不同地区胆结石病 (GSD) 的流行情况.
- 根据性别,年龄和胆囊癌 (GBC) 的地理风险分析GSD患病率.
- 估计高风险和低风险GBC地区GSD的种群可归因分数 (PAF).
主要方法:
- 一项基于社区的横截面研究,涉及28395名30-65岁的参与者.
- 采用结构化采访,从高风险 (Kamprup,Silchar,Mullanpur,Varanasi) 和低风险 (Barshi) GBC地区收集自我报告的胆结石史.
- 对GSD的流行率和人口归因分数 (PAF) 被计算并按性别,年龄和地区分层.
主要成果:
- 胆结石的发病率在穆兰普尔 (10.8%) 和坎普鲁普 (10.7%) 最高,在巴尔西 (0.3%) 最低.
- 在高风险GBC地区的女性中,随着年龄的增长观察到胆结石患病率的增加.
- 在高风险GBC地区,GSD的种群可归因分数 (PAF) 为2.7%,在低风险地区为0.2%.
结论:
- 严重的区域性和基于性别的GSD患病率变化与印度高风险GBC区域相关.
- 调查结果强调需要在高风险地区制定有针对性的监测计划.
- 进一步的病因学研究是有必要的,以了解GSD的驱动因素及其与GBC的联系.
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