在印度第三级护理中心接受治疗的前列腺癌患者的生存结果
Aswathy P1,2,3,4,5, Sivaranjini Kannusamy1,2,3,4,5, Amey Oak1,2,3,4,5
1Homi Bhabha National Institute Mumbai India.
BJUI compass
|February 9, 2026
概括
印度的前列腺癌存活率在5年内为61%,受疾病阶段,PSA,格里森等级和治疗的影响. 早期发现和治疗完成对于改善患者的治疗结果至关重要.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 前列腺癌在印度构成了日益严重的公共卫生挑战.
- 前列腺癌患者的生存结果存在显著差异.
- 这项研究侧重于在孟买塔塔纪念医院 (TMH) 接受治疗的前列腺癌患者.
研究的目的:
- 评估印度前列腺癌患者的5年整体生存率.
- 确定影响这一群体生存的关键预后因素.
- 为改善印度前列腺癌护理的策略提供信息.
主要方法:
- 2017年1月至12月期间在TMH诊断和治疗的421名前列腺癌患者的回顾性分析.
- 数据收集包括临床流行病学变量:年龄,PSA水平,格里森等级,临床程度,治疗意图,完成和方式.
- 卡普兰-梅尔曲线和考克斯比例危险模型被用来分析生存结果.
主要成果:
- 整体5年生存率为61%.
- 显著的预后因素包括年龄,PSA水平,格里森等级和疾病程度 (局部,局部进展,转移性).
- 转移性疾病 (41%的5年生存率),高PSA (>1000 ng/ml,33%的生存率) 和不完整的治疗 (12%的生存率) 与较差的结果有关,而治疗意图 (81%的生存率) 和治疗完成 (65%的生存率) 改善了生存率.
结论:
- 前列腺癌的存活率受到疾病程度,PSA和格里森等级等诊断因素以及治疗相关因素,如意图,完成和方式等因素的显著影响.
- 提高早期检测方法对于提高生存率至关重要.
- 扩大多式联络治疗策略和确保治疗坚持是印度前列腺癌患者获得更好的治疗结果的关键.
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