在预测过度活跃膀风险方面,METS-VF优于传统的脂肪指数:基于NHANES的横截面研究
Ping Cai1, Fu Feng2,3, Zhanping Xu2,3
1Division 3, Concord Medical Center, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences) Southern Medical University, Guangzhou, China.
Translational andrology and urology
|February 9, 2026
概括
以内脏脂肪代谢得分 (METS-VF) 衡量内脏脂肪的内脏脂肪,与过度活性膀 (OAB) 风险有显著联系. METS-VF对OAB的预测能力比传统的肥胖指标更强.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 代谢健康 代谢健康
- 公共卫生 公共卫生
背景情况:
- 过度活性膀 (OAB) 是一种常见的尿道疾病,其原因复杂.
- 内脏脂肪在OAB病变中的作用尚不清楚.
研究的目的:
- 调查美国人口内脏脂肪代谢得分 (METS-VF) 与OAB风险之间的关联.
- 将METS-VF的预测效用与OAB的传统脂肪指数进行比较.
主要方法:
- 全国健康和营养检查调查 (NHANES) 对6366名参与者的数据进行了横截面分析.
- 使用多变量逻辑回归,子组分析和ROC分析.
- 将METS-VF的预测能力与BMI,WC和WHtR进行比较.
主要成果:
- 在METS-VF和OAB之间发现了显著的联系 (P<0.001),在METS-VF四分位数中,患病率增加.
- 在完全调整后,METS-VF仍然与OAB显著相关 (OR=1.38,95% CI:1.22-1.57).
- 与BMI,WC和WHtR相比,METS-VF显示OAB的预测能力优越.
结论:
- METS-VF是美国成年人OAB风险的强有力的预测指标.
- METS-VF的增强预测能力表明,临床风险评估和针对内脏肥胖的公共卫生战略有潜力.
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